RNF8 antibody

Principal name

RNF8 antibody

Alternative names for RNF8 antibody

RING finger protein 8, E3 ubiquitin-protein ligase RNF8

SwissProt ID

O76064 (Human), Q2HJ46 (Bovin), Q4KLN8 (Rat), Q803C1 (Danre), Q8VC56 (Mouse)

Gene ID

9025 (RNF8)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), African clawed frog, Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Dot blot (Dot), Immunoprecipitation (IP)

Background of RNF8 antibody

The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase. It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation. The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, and they co-localize in the nucleus. RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains. RNF8 also binds to Retinoid X receptor alpha (RXR?, a member of the steroid hormone receptor superfamily. It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity.

General readings

Seki N, Hattori A, Sugano S, Suzuki Y, Nakagawara A, Ohhira M, Muramatsu M, Hori T, Saito T.
Isolation, tissue expression, and chromosomal assignment of a novel human gene which encodes a protein with RING finger motif.
J Hum Genet. 1998;43(4):272-4.
PMID: 9852682

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNF8 control peptide

RNF8
50 µg / €160.00
  Acris Antibodies GmbH

RNF8 (N-term) antibody

TA302855 staining (0.1µg/ml) of Human Lung lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF8 (C-term) antibody

Western blot analysis of RNF8 in human lung tissue lysate with RNF8 antibody at (A) and (B) 2 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF8 antibody

RNF8 Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF8 antibody

Western blot analysis of RNF8 Antibody (Cat. #AP53695PU-N) in Jurkat cell line lysates (35µg/lane). RNF8 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RNF8 antibody

Immunofluorescence of purified MaxPab antibody to RNF8 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

RNF8 antibody

Immunofluorescence of purified MaxPab antibody to RNF8 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

RNF8 antibody

Western Blot analysis of RNF8 expression in transfected 293T cell line (H00009025-T02) by RNF8 MaxPab polyclonal antibody.

Lane 1: RNF8 transfected lysate(55.50 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

RNF8 antibody

RNF8 polyclonal antibody ( Cat # PAB6337 ) staining ( 0.1 µg/ml ) of human lung lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

RNF8 antibody

Human Heart; RNF8 antibody - C-terminal region (ARP40071_T100) in Human Heart cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

RNF8 antibody

NB 100-1176 staining (0.1µg/ml) of Human Lung lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

RNF8 antibody

Immunofluorescence: RNF8 Antibody [NBP1-30926] - Immunofluorescence analysis of HeLa, using NBP1-30926 at 1:200 dilution. Rabbit IgG Hu Dot, ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

RNF8 antibody

Immunofluorescence: RNF8 Antibody [NBP1-77166] - Rat lung tissue with RNF8 antibody at 20 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNF8

RNF8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RNF8

RNF8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RNF8 293T Cell Transient Overexpression Lysate(Denatured)

RNF8 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

RNF8 overexpression lysate

RNF8 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

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