RP1 / ORP1 antibody

Principal name

RP1 / ORP1 antibody

Alternative names for RP1 / ORP1 antibody

Retinitis pigmentosa 1 protein, Retinitis pigmentosa RP1 protein, Oxygen-regulated protein 1

SwissProt ID

P56715, P56716, Q8MJ04, Q8MJ05

Gene ID

6101 (RP1), 19888 (Rp1)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of RP1 / ORP1 antibody

Retinitis pigmentosa 1 (RP1), also known as oxygen-regulated protein 1, retinitis pigmentosa 1 protein, ORP1, and DCDC4A, regulates the stability and length of microtubule based axoneme of photoreceptors. RP1 is critical for the differentiation of photoreceptor cells, and RP1 also influences the photosensitivity and outer segment morphogenesis of rod photoreceptors. Similarly, RP1 controls the correct orientation and higher order stacking of the outer segment disks along the photoreceptor axoneme. RP1 is found in the cytoplasm and has only been reported in the reti. RP1 is subject to phosphorylation, and mutations in RP1 cause autosomal recessive and domint retinitis pigmentosa. Both of these diseases lead to degeneration of the retil photoreceptor cells resulting in night blindness, loss of peripheral visual field, and eventually loss of central vision (PMID: 10391211).

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RP1 / ORP1 antibody

Immunohistochemistry: RP1 Antibody [TA336927] - IHC analysis of RP1 in mouse retina. Rabbit Purified Hu, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

RP1 - human gene knockout kit via CRISPR

RP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RP1 - human gene knockout kit via CRISPR

RP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RP1 - human gene knockout kit via CRISPR

RP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RP1 - human gene knockout kit via CRISPR

RP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rp1 - mouse gene knockout kit via CRISPR

Rp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rp1 - mouse gene knockout kit via CRISPR

Rp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rp1 - mouse gene knockout kit via CRISPR

Rp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rp1 - mouse gene knockout kit via CRISPR

Rp1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rp1 (GFP-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Rp1 (GFP-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rp1 (Myc-DDK-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Rp1 (Myc-DDK-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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