RPS6KB1 / STK14A antibody

Principal name

RPS6KB1 / STK14A antibody

Alternative names for RPS6KB1 / STK14A antibody

Ribosomal protein S6 kinase I, S6K1, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, Serine/threonine-protein kinase 14A, Ribosomal protein S6 kinase beta-1, S6K-beta-1, 70 kDa ribosomal protein S6 kinase 1, 70 kDa ribosomal protein S6 kinase 1, p70-S6K 1

SwissProt ID

P23443 (Human), P67998 (Rabit), P67999 (Rat), Q6TJY3 (Bovin), Q8BSK8 (Mouse)

Gene ID

6198 (RPS6KB1), 83840 (Rps6kb1), 72508

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Can (Canine), Por (Porcine), Rb (Rabbit), Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F)

Background of RPS6KB1 / STK14A antibody

Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway. Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. During translation initiation, the inactive form associatess with the eIF-3 complex under conditions of nutrient depletion. Mitogenic stimulation leads to phosphorylation and dissociation from the eIF-3 complex and the free activated form can phosphorylate other translational targets including EIF4B. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation. Phosphorylates RICTOR leading to regulation of mammalian target of rapamycin complex 2 (mTORC2) signaling; probably phosphorylates RICTOR at 'Thr-1135'. Phosphorylates IRS1 at multiple serine residues coupled with insulin resistance; probably phosphorylates IRS1 at 'Ser-270'. Required for TNF-alpha induced IRS-1 degradation. Phosphorylates EEF2K in response to IGF1 and inhibits EEF2K activity. Phosphorylates BAD at 'Ser-99' in response to IGF1 leading to BAD inactivation and inhibition of BAD-induced apoptosis. Phosphorylates mitochondrial RMP leading to dissociation of a RMP:PPP1CC complex; probably phosphorylates RMP at 'Ser-99'. The free mitochondrial PPP1CC can dephosphorylate RPS6KB1 at Thr-412 which is proposed to be a negative feed back mechanism for the RPS6KB1 antiapoptotic function. Phosphorylates GSK3B at 'Ser-9' under conditions leading to loss of the TSC1-TSC2 complex. Phosphorylates POLDIP3.

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 28 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RPS6KB1 / STK14A antibody

  RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-RPS6KB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502929) Mouse IgG1 OTI6B2 Purified Can, Hu, Mky, Ms ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

RPS6KB1 / STK14A antibody

  RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI1G4 (formerly 1G4)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-RPS6KB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502913) Mouse IgG1 OTI1G4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

RPS6KB1 / STK14A antibody

  Anti-RPS6KB1 (Phospho-Ser411) Rabbit Polyclonal Antibody  
Predicted band size: 70; 85 kDa . Positive control: MCF cells treated with EGF lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: MCF cells untreated with EGF lysate Lane2: MCF cells treated with EGF lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

RPS6KB1 / STK14A antibody

  Anti-RPS6KB1 (Phospho-Ser424) Rabbit Polyclonal Antibody  
Predicted band size: 70; 85 kDa . Positive control: MCF cells treated with EGF lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: MCF cells untreated with EGF lysate Lane2: MCF cells treated with EGF lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

RPS6KB1 / STK14A antibody

  RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4)  
Anti-RPS6KB1 mouse monoclonal antibody (TA502930) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RPS6KB1(RC217324 ). Mouse IgG1 OTI4G4 Purified Hu F, ICC/IF, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

RPS6KB1 / STK14A pThr421 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase pThr421 antibody AP02506PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A pThr421 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase pThr421 antibody AP02506PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µg / €240.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A pSer411 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using p70 S6 Kinase pSer411 antibody AP02516PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A pSer411 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using p70 S6 Kinase pSer411 antibody AP02516PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µg / €240.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Figure 2. Immunofluorescence staining of methanol-fixed HeLa cells using p70 S6 kinase antibody AP02697PU (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Figure 2. Immunofluorescence staining of methanol-fixed HeLa cells using p70 S6 kinase antibody AP02697PU (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µg / €240.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase antibody. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase antibody. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µg / €240.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using p70 S6 Kinase antibody. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using p70 S6 Kinase antibody. Rabbit Aff - Purified Hu ICC/IF, P, WB
50 µg / €240.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemistry (IHC) analyzes of p70 S6K antibody (Cat.-No.: AP06552PU-N) in paraffin-embedded human breast tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemistry (IHC) analyzes of p70 S6K antibody (Cat.-No.: AP06554PU-N) in paraffin-embedded humanbreast carcinomatissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemistry analyzes of p70 S6K antibody (Cat.-No.: AP20732PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A antibody

Immunohistochemistry analyzes of p70 S6K antibody (Cat.-No.: AP20734PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

RPS6KB1 / STK14A pThr444 antibody

Immunohistochemistry (IHC) analyzes of p-p70 S6 kinase alpha antibody (Cat.-No.: AP20853PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

Items 1 to 20 of 28 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn