RRM1 / RR1 antibody

Principal name

RRM1 / RR1 antibody

Alternative names for RRM1 / RR1 antibody

Ribonucleotide reductase large subunit, Ribonucleotide reductase M1, Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1

SwissProt ID

P00452 (Ecoli), P07742 (Mouse), P21524 (Yeast), P23921 (Human), P36602 (Schpo), P48591 (Drome), P79732 (Danre), Q03604 (Caeel), Q9SJ20 (Arath)

Gene ID

6240 (RRM1), 856801 (RNR1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Ce (C. elegans), S. cerevisiae (Saccharomyces cerevisiae)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of RRM1 / RR1 antibody

RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes one of two non-identical subunits which constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. This gene is oriented in a head-to-tail configuration with the stromal interaction molecule 1 gene (STIM1), with the 3\' end of STIM1 situated 1.6 kb from the 5\' end of this gene.

General readings

Bryan,B.A., J. Gen. Virol. 87 (PT 3), 519-529 (2006)

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  2. Highly Validated (4)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody,clone UMAB165  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RRM1 mouse monoclonal antibody. (UM800059; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 UMAB165 Purified Hu P
0.1 ml / €379.00
  OriGene Technologies, Inc.

UltraMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody,clone UMAB165  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RRM1 mouse monoclonal antibody. (UM800059; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 UMAB165 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

RRM1 / RR1 antibody

  Rabbit Monoclonal anti-RRM1 Antibody  
Human Lung Adenocarcinoma stained with anti-RRM1 antibody . Rabbit SP167 Purified Hu F, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI5G5 (formerly 5G5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801208) Mouse IgG1 OTI5G5 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  Anti-RRM1 Rabbit Polyclonal Antibody  
Predicted band size: 90 kDa . Positive control: Hela and 231 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Hela cell lysate Lane2: 231 cell lysate Lysates: 50 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RRM1 / RR1 antibody

  Anti-RRM1 Rabbit Polyclonal Antibody  
Predicted band size: 90 kDa . Positive control: Hela cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RRM1 / RR1 antibody

  RRM1 Rabbit Polyclonal Antibody  
Western blot analysis of A549 cell and SH-SY5Y cell lysate using RRM1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

RRM1 / RR1 antibody

  Rabbit Polyclonal anti-RRM1 Antibody  
Human Placenta stained with anti-RRMI antibody. Rabbit Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI13E4 (formerly 13E4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RRM1 (RC200726, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RRM1. Mouse IgG1 OTI13E4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI3G5 (formerly 3G5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RRM1 (RC200726, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RRM1. Mouse IgG1 OTI3G5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9)  
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804454) Mouse IgG1 OTI1F9 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI12B9 (formerly 12B9)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RRM1 (RC200726, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RRM1. Mouse IgG2a OTI12B9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI16A8 (formerly 16A8)  
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-RRM1 Mouse monoclonal antibody. (TA804537; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI16A8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI9A2 (formerly 9A2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RRM1 (RC200726, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RRM1. Mouse IgG1 OTI9A2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI17C3 (formerly 17C3)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804723) Mouse IgG1 OTI17C3 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RRM1 / RR1 antibody

  RRM1 mouse monoclonal antibody, clone OTI2D10 (formerly 2D10)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804875) Mouse IgG1 OTI2D10 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RRM1 / RR1

  Recombinant protein of human ribonucleotide reductase M1 (RRM1)  
RRM1 / RR1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

RRM1 overexpression lysate

RRM1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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