RSAD2 / CIG5 antibody

Principal name

RSAD2 / CIG5 antibody

Alternative names for RSAD2 / CIG5 antibody

Viperin, VIG1, CIG33, Radical S-adenosyl methionine domain-containing protein 2, Cytomegalovirus-induced gene 5 protein, Virus inhibitory protein endoplasmic reticulum-associated interferon-inducible

SwissProt ID

O70600 (Rat), Q2HJF9 (Bovin), Q3UDI0 (Mouse), Q5RH95 (Danre), Q8CBB9 (Mouse), Q8WXG1 (Human), Q9MZU4 (Pig)

Gene ID

91543 (RSAD2), 58185 (Rsad2), 65190

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RSAD2 / CIG5 antibody

Viperin is a 42 kDa protein belonging to the RSAD2 family.
Viperin is the abbreviation of Virus inhibitory protein endoplasmic reticulum-associated interferon-inducible. It is an evolutionary conserved protein that is highly inducible by both type I and type II interferons. However, little or no induction by interferon gamma is observed in monocytic cell lines. Infection by many viruses, including human cytomegalovirus (hCMV), hepatitis C virus, yellow fever virus and Sendai virus, strongly induces viperin expression, suggesting a role in the host antiviral response. Viperin has also been shown to be important for the host anti-HIV responses. Furthermore, expression of viperin inhibits influenza replication by perturbing its release from the plasma membrane. Viperin expression alters plasma membrane fluidity by affecting formation of lipid rafts which are detergent-resistant membrane microdomains known to be the sites of influenza virus budding. HCMV infection induces the redistribution of viperin from the endoplasmic reticulum to the Golgi complex and ultimately to cytoplasmic vacuoles, suggesting that viperin may function at a distinct level in the viral lifecycle, at the point of glycosylated viral protein transport.

General readings

Helbig,K.J., (2005) Hepatology 42 (3), 702-710

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RSAD2 / CIG5 antibody

  Rabbit Polyclonal anti-RSAD2 antibody  
WB Suggested Anti-RSAD2 Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RSAD2 / CIG5 antibody

  Rabbit Polyclonal anti-RSAD2 antibody  
WB Suggested Anti-RSAD2 Antibody Titration: 5.0 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RSAD2 / CIG5 antibody

  RSAD2 mouse monoclonal antibody, clone OTI4D12 (formerly 4D12)  
Anti-RSAD2 mouse monoclonal antibody (TA505799) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RSAD2(RC205066). Mouse IgG2b OTI4D12 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

RSAD2 / CIG5 (92-362) antibody

RSAD2 / CIG5 Mouse IgG2a MaP.VIP Purified Hu, Ms ICC/IF, IP, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

RSAD2 - human gene knockout kit via CRISPR

RSAD2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RSAD2 - human gene knockout kit via CRISPR

RSAD2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RSAD2 - human gene knockout kit via CRISPR

RSAD2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RSAD2 - human gene knockout kit via CRISPR

RSAD2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rsad2 - mouse gene knockout kit via CRISPR

Rsad2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rsad2 - mouse gene knockout kit via CRISPR

Rsad2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rsad2 - mouse gene knockout kit via CRISPR

Rsad2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rsad2 - mouse gene knockout kit via CRISPR

Rsad2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RSAD2 / CIG5

  Recombinant protein of human radical S-adenosyl methionine domain containing 2 (RSAD2)  
RSAD2 / CIG5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

RSAD2 overexpression lysate

RSAD2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RSAD2 (mGFP-tagged) - Human radical S-adenosyl methionine domain containing 2 (RSAD2), 200 uL, >10^7 TU/mL

Lenti ORF particles, RSAD2 (mGFP-tagged) - Human radical S-adenosyl methionine domain containing 2 (RSAD2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, RSAD2 (Myc-DDK tagged) - Human radical S-adenosyl methionine domain containing 2 (RSAD2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, RSAD2 (Myc-DDK tagged) - Human radical S-adenosyl methionine domain containing 2 (RSAD2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rsad2 (GFP-tagged ORF) - Rat radical S-adenosyl methionine domain containing 2 (Rsad2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rsad2 (GFP-tagged ORF) - Rat radical S-adenosyl methionine domain containing 2 (Rsad2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rsad2 (Myc-DDK-tagged ORF) - Rat radical S-adenosyl methionine domain containing 2 (Rsad2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rsad2 (Myc-DDK-tagged ORF) - Rat radical S-adenosyl methionine domain containing 2 (Rsad2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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