RSAD2 / CIG5 antibody

Principal name

RSAD2 / CIG5 antibody

Alternative names for RSAD2 / CIG5 antibody

Viperin, VIG1, CIG33, Radical S-adenosyl methionine domain-containing protein 2, Cytomegalovirus-induced gene 5 protein, Virus inhibitory protein endoplasmic reticulum-associated interferon-inducible

SwissProt ID

O70600 (Rat), Q2HJF9 (Bovin), Q3UDI0 (Mouse), Q5RH95 (Danre), Q8CBB9 (Mouse), Q8WXG1 (Human), Q9MZU4 (Pig)

Gene ID

91543 (RSAD2)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of RSAD2 / CIG5 antibody

The monoclonal antibody MaP.VIP recognizes mouse Viperin, a 42 kDa protein belonging to the RSAD2 family. Viperin is the abbreviation of Virus inhibitory protein endoplasmic reticulum-associated interferon-inducible. It is an evolutionary conserved protein that is highly inducible by both type I and type II interferons. However, little or no induction by interferon gamma is observed in monocytic cell lines. Infection by many viruses, including human cytomegalovirus (hCMV), hepatitis C virus, yellow fever virus and Sendai virus, strongly induces viperin expression, suggesting a role in the host antiviral response. Viperin has also been shown to be important for the host anti-HIV responses. Furthermore, expression of viperin inhibits influenza replication by perturbing its release from the plasma membrane. Viperin expression alters plasma membrane fluidity by affecting formation of lipid rafts which are detergent-resistant membrane microdomains known to be the sites of influenza virus budding. HCMV infection induces the redistribution of viperin from the endoplasmic reticulum to the Golgi complex and ultimately to cytoplasmic vacuoles, suggesting that viperin may function at a distinct level in the viral lifecycle, at the point of glycosylated viral protein transport.

General readings

Helbig,K.J., (2005) Hepatology 42 (3), 702-710

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RSAD2 / CIG5 antibody

Anti-RSAD2 mouse monoclonal antibody (TA505799) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RSAD2(RC205066). Mouse IgG2b OTI4D12 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

RSAD2 / CIG5 (92-362) antibody

RSAD2 / CIG5 Mouse IgG2a MaP.VIP Purified Hu, Ms ICC/IF, IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

RSAD2 / CIG5 antibody

RSAD2 / CIG5 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

RSAD2 / CIG5 antibody

RSAD2 / CIG5 Mouse IgG2a 4D10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RSAD2 / CIG5 antibody

Human Jurkat; WB Suggested Anti-RSAD2 Antibody Titration: 2.5ug/ml. Positive Control: Jurkat cell lysate; RSAD2 antibody - N-terminal region (ARP42695_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

RSAD2 / CIG5 antibody

Human kidney; RSAD2 antibody - C-terminal region (ARP42696_T100) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

RSAD2 / CIG5 antibody

RSAD2 / CIG5 Mouse IgG2a MaP.VIP Aff - Purified Hu, Ms F, ICC/IF, IP, WB
0.1 mg / €670.00
  Novus Biologicals Inc.

RSAD2 / CIG5 antibody

RSAD2 / CIG5 Mouse IgG2a MaP.VIP Aff - Purified Hu, Ms F, ICC/IF, IP, WB
50 µg / €400.00
  Novus Biologicals Inc.

RSAD2 / CIG5 antibody

RSAD2 / CIG5 Mouse IgG2a MaP.VIP Aff - Purified Hu F, ICC/IF, IP, WB
0.1 mg / €670.00
  Novus Biologicals Inc.

RSAD2 / CIG5 antibody

RSAD2 / CIG5 Mouse IgG2a MaP.VIP Aff - Purified Hu F, ICC/IF, IP, WB
50 µg / €400.00
  Novus Biologicals Inc.

RSAD2 / CIG5 antibody

Immunohistochemistry-Paraffin: Viperin Antibody [NBP1-58021] - Human kidney, epithelial cells of renal tubule (indicated with arrows). Rabbit Purified Bov, Can, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

RSAD2 / CIG5 antibody

Western Blot: Viperin Antibody [NBP1-58062] - This Anti-RSAD2 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 2.5ug/ml. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €360.00
  Novus Biologicals Inc.

RSAD2 / CIG5 antibody

Immunohistochemistry-Paraffin: Viperin Antibody [NBP1-84467] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Western Blot/IP/ChiP Kits

Catalog No. Host Iso. Clone Pres. React. Applications  

RSAD2 Western Blot kit

RSAD2 Western Blot kit
1 kit / €640.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RSAD2 / CIG5

RSAD2 / CIG5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

RSAD2 / CIG5

RSAD2 / CIG5 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

RSAD2 / CIG5

RSAD2 / CIG5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

RSAD2 / CIG5

RSAD2 / CIG5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RSAD2 293T Cell Transient Overexpression Lysate(Denatured)

RSAD2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

RSAD2 overexpression lysate

RSAD2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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