RSPO1 antibody

Principal name

RSPO1 antibody

Alternative names for RSPO1 antibody

R-spondin-1, Roof plate-specific spondin-1

SwissProt ID

Q2MKA7 (Human), Q6DHR0 (Danre), Q9Z132 (Mouse)

Gene ID

284654 (RSPO1), 192199 (Rspo1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of RSPO1 antibody

R-spondin1, also known as RSPO1, CRISTIN3, FLJ40906. Entrez Protein NP_001033722.1. It is a member of the R-spondin family and a 28.9kDa secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestil epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.It is activator of the beta-catenin sigling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor sigling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determition.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RSPO1 antibody

  Rabbit Polyclonal RSPO1 Antibody  
Western blot analysis of RSPO1 in rat spleen tissue lysate with RSPO1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RSPO1 antibody

  Rabbit Polyclonal RSPO1 Antibody  
ELISA: RSPO1 Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

RSPO1 antibody

  Purified RSPO1 mouse monoclonal antibody, clone OTI2B11 (formerly 2B11)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RSPO1 (RC217921, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RSPO1. Mouse IgG2a OTI2B11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RSPO1 antibody

  Purified RSPO1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RSPO1 (RC217921, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RSPO1. Mouse IgG1 OTI2F10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RSPO1 antibody

  RSPO1 mouse monoclonal antibody, clone OTI11A9 (formerly 11A9)  
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-RSPO1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804626) Mouse IgG2b OTI11A9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RSPO1 antibody

  RSPO1 mouse monoclonal antibody, clone OTI1C3 (formerly 1C3)  
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-RSPO1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804766) Mouse IgG1 OTI1C3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RSPO1 antibody

Western blot analysis using R-spondin1 mouse mAb against recombinant R-spondin1 protein (Lane 1) and R-spondin1(aa21-263)-hIgGFc transfected HEK293 cell lysate (Lane 2). Mouse IgG1 7A6 Ascites Hu WB
0.1 ml / €400.00
  Acris Antibodies GmbH

RSPO1 (N-term) antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

RSPO1 - human gene knockout kit via CRISPR

RSPO1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RSPO1 - human gene knockout kit via CRISPR

RSPO1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RSPO1 - human gene knockout kit via CRISPR

RSPO1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RSPO1 - human gene knockout kit via CRISPR

RSPO1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rspo1 - mouse gene knockout kit via CRISPR

Rspo1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rspo1 - mouse gene knockout kit via CRISPR

Rspo1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rspo1 - mouse gene knockout kit via CRISPR

Rspo1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rspo1 - mouse gene knockout kit via CRISPR

Rspo1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RSPO1

  Purified recombinant protein of Human R-spondin homolog (Xenopus laevis) (RSPO1).  
RSPO1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
CHO cells

Regular Price: 20 µg / €399.00

Special Price: 20 µg / €239.00

  OriGene Technologies, Inc.

RSPO1

RSPO1 Human Purified > 95 % by SDS-PAGE and HPLC CHO cells
20 µg / €330.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

RSPO1 overexpression lysate

RSPO1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RSPO1 (mGFP-tagged) - Human R-spondin homolog (Xenopus laevis) (RSPO1), 200 uL, >10^7 TU/mL

Lenti ORF particles, RSPO1 (mGFP-tagged) - Human R-spondin homolog (Xenopus laevis) (RSPO1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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