RSPO2 antibody

Principal name

RSPO2 antibody

Alternative names for RSPO2 antibody

R-spondin-2, Roof plate-specific spondin-2

SwissProt ID

Q5UE90 (Xenla), Q6UXX9 (Human), Q8BFU0 (Mouse)

Gene ID

340419 (RSPO2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P)

Background of RSPO2 antibody

The R-Spondin (Rspo) proteins belong to the Rspo family of Wnt modulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. The Rspo proteins can interact with the Frizzled/LRP6 receptor complex in a manner that causes the stabilization and resulting accumulation of the intracellular signaling protein, β-catenin. This activity effectively activates and increases the subsequent nuclear signaling of β-catenin. R-Spondin can also bind to the previously discovered G-protein coupled receptors, LGR-4 and LGR-5. Rspo/β-catenin signaling can act as an inducer of the transformed phenotype, and can also regulate the proliferation and differentiation of certain stem cell populations.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RSPO2 antibody

Immunohistochemistry-Paraffin: RSPO2 Antibody [NBP1-81093] Immunohistochemical staining of human pancreas shows cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RSPO2

RSPO2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
CHO cells

Regular Price: 20 µg / €399.00

Special Price: 20 µg / €239.00

  OriGene Technologies, Inc.

RSPO2

RSPO2 Human Purified > 95 % by SDS-PAGE and HPLC CHO cells
20 µg / €330.00
  Acris Antibodies GmbH

RSPO2

RSPO2 Human
2 µg / €300.00
  Abnova Taiwan Corp.

RSPO2

RSPO2 Human
20 µg / €450.00
  Abnova Taiwan Corp.

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