RUNX1T1 antibody

Principal name

RUNX1T1 antibody

Alternative names for RUNX1T1 antibody

AML1T1, CBFA2T1, MTG8, ZMYND2, Cyclin-D-related protein, CDR, Eight twenty one protein, ETO, Zinc finger MYND domain-containing protein 2

SwissProt ID

Q06455 (Human), Q61909 (Mouse), Q92479 (Human)

Gene ID

862 (RUNX1T1), 12395 (Runx1t1)

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of RUNX1T1 antibody

RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.

General readings

Lausen,J., et al., (2004) J. Biol. Chem. 279 (47), 49281-49288

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RUNX1T1 antibody

  Rabbit Polyclonal Anti-RUNX1T1 Antibody  
1Human 721_B; Host: Rabbit; Target Name: WT1; Sample Tissue: 721_B; Antibody Dilution: 1.0 ug/mlRUNX1T1 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit Aff - Purified African clawed frog, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RUNX1T1 antibody

  Rabbit Polyclonal Anti-RUNX1T1 Antibody - middle region  
WB Suggested Anti-RUNX1T1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

RUNX1T1 antibody

  Rabbit Polyclonal ETO Antibody  
ChIP assays were performed using SKNO-1 cells, the antibody against ETO and optimized primer pairs for qPCR. Sheared chromatin from 1.25 million cells and 4 ul of antibody were used per ChIP experiment. QPCR was performed using primers specific for the FUT7, NFE2, OGG1 and VEGF genes. Image shows the occupancy, calculated as the ratio + control/background for which the H2B gene was used. Rabbit IgG Purified Hu E
0.1 ml / €325.00
  OriGene Technologies, Inc.

RUNX1T1 antibody

  Rabbit Polyclonal AML-ETO Antibody  
WB was performed on seven GST-fusion proteins containing different fragments of AML-ETO (1-7) with the ab at 1:1,000. The antibody raised against AML-ETO recognizes the ETO part (lane 2) of the fusion protein. C: WB was performed on nuclear extracts from KAS-6/1 cells (human myeloma cell line) and SKNO-1 cells (human acute myeloblastic leukaemia) with the ab against AML-ETO at 1:1,000 . The location of AML-ETO and a presumed splice variant (missing 106 C-terminal amino acids) are indicated. Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

RUNX1T1 antibody

  Rabbit Polyclonal Anti-RUNX1T1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (RUNX1T1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

RUNX1T1 antibody

  RUNX1T1 (ETO) mouse monoclonal antibody, clone OTI1H1 (formerly 1H1)  
Anti-RUNX1T1 mouse monoclonal antibody (TA504703) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RUNX1T1(RC222426). Mouse IgG1 OTI1H1 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

RUNX1T1 antibody

  Rabbit Polyclonal RUNX1T1/ETO Antibody  
ELISA: RUNX1T1 / ETO Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

Runx1t1 - mouse gene knockout kit via CRISPR

Runx1t1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Runx1t1 - mouse gene knockout kit via CRISPR

Runx1t1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Runx1t1 - mouse gene knockout kit via CRISPR

Runx1t1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Runx1t1 - mouse gene knockout kit via CRISPR

Runx1t1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RUNX1T1 (transcript variant 4)

  Recombinant protein of human runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 4  
RUNX1T1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

RUNX1T1 (transcript variant 3)

  Recombinant protein of human runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3  
RUNX1T1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

RUNX1T1 overexpression lysate

RUNX1T1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

RUNX1T1 overexpression lysate

RUNX1T1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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