RUNX3 antibody

Principal name

RUNX3 antibody

Alternative names for RUNX3 antibody

Runt-related transcription factor 3, AML2, CBFA3, CBF-alpha-3, PEBP2A3, PEBP2-alpha C, PEA2-alpha C, Core-binding factor subunit alpha-3, Acute myeloid leukemia 2 protein, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit

SwissProt ID

Q13761 (Human), Q64131 (Mouse)

Gene ID

864 (RUNX3)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Chk (Chicken), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of RUNX3 antibody

The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3), and belongs to the acute myeloid leukemia (AML) family. RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX3 is expressed in cells of hematopoietic origin, including myeloid and B-cell lines and spleen. By playing a role in controlling the growth and differentiation of gastric epithelial cells, RUNX3 is a strong candidate as a gastric cancer tumor suppressor. Specifically, hypermethylation inactivates the gene encoding RUNX3. The detection of hypermethylation at multiple regions within the RUNX3 CpG island may aid in the diagnosis and risk assessment of gastric cancer.

General readings

Vogiatzi P. et al. (2006) Cancer Biol Ther. 5(4):371-4.
Li QL,et al. (2002)Cell. 109(1):113-24.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RUNX3 antibody

  Rabbit polyclonal anti-RUNX3 antibody  
Western blot analysis of extracts from 293/HeLa cells, using RUNX3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RUNX3 antibody

  Anti-RUNX3 rabbit polyclonal antibody  
Predicted band size: 44kDa. Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RUNX3 antibody

  Anti-RUNX3 rabbit polyclonal antibody  
Predicted band size: 44kDa. Positive control: Mouse thymus tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RUNX3 (Center) antibody

  Rabbit polyclonal RUNX3 Antibody (Center)  
Western blot analysis of lysates from HL-60,  Jurkat cell line (from left to right),  using RUNX3 Antibody (Center) (Cat.   #TA324560).  TA324560 was diluted at 1:1000 at each lane.  A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.  Lysates at 35ug per lane. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

RUNX3 antibody

  Rabbit Polyclonal Anti-RUNX3 Antibody  
WB Suggested Anti-RUNX3 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:12500; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RUNX3 antibody

Western blot analysis of RUNX3 antibody (Cat.-No.: AP20638PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

RUNX3 - human gene knockout kit via CRISPR

RUNX3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RUNX3 - human gene knockout kit via CRISPR

RUNX3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RUNX3 - human gene knockout kit via CRISPR

RUNX3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RUNX3 - human gene knockout kit via CRISPR

RUNX3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RUNX3 (full length, N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human runt-related transcription factor 3 (RUNX3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
RUNX3 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

RUNX3 (53-186, His-tag)

RUNX3 Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / €750.00
  Acris Antibodies GmbH

RUNX3 (53-186, His-tag)

RUNX3 Human Purified > 95 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RUNX3 (mGFP-tagged) - Human runt-related transcription factor 3 (RUNX3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, RUNX3 (mGFP-tagged) - Human runt-related transcription factor 3 (RUNX3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, RUNX3 (Myc-DDK tagged) - Human runt-related transcription factor 3 (RUNX3), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, RUNX3 (Myc-DDK tagged) - Human runt-related transcription factor 3 (RUNX3), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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