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RXR-beta / RXRB antibody

Principal name

RXR-beta / RXRB antibody

Alternative names for RXR-beta / RXRB antibody

NR2B2, H-2RIIBP, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta, Nuclear receptor subfamily 2 group B member 2, Nuclear Receptor Coregulator 1

SwissProt ID

P28702 (Human), P28704 (Mouse), P49743 (Rat), Q5TJF7 (Canfa)

Gene ID

6257 (RXRB), 20182 (Rxrb)

Ncbi ID

9606, NP_068811, NP_068811.1, NP_001192145.1, NM_011306, NM_021976

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of RXR-beta / RXRB antibody

RXRB is a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Samad TA, Krezel W, Chambon P, Borrelli E.
Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14349-54.

Western Blot analysis of RXRB expression in transfected 293T cell line (H00006257-T01) by RXRB MaxPab polyclonal antibody.Lane 1: RXRB transfected lysate(58.63 KDa).Lane 2: Non-transfected lysate.

H00006257-B01

RXRB polyclonal antibody ( Cat # PAB6693 ) staining ( 1 µg/ml ) of A-431 lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

PAB6693

HEK293 overexpressing RXRB and probed with RXRB polyclonal antibody ( Cat # PAB6693 ) ( mock transfection in first lane ), tested by Origene.

PAB6693

Western Blot analysis of RXRB expression in transfected 293T cell line by RXRB monoclonal antibody (M01), clone 3C8.Lane 1: RXRB transfected lysate(56.9 KDa).Lane 2: Non-transfected lysate.

H00006257-M01

Human Placenta; WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Placenta; RXRB antibody - C-terminal region (ARP39524_P050) in Human Placenta cells using Western Blot

ARP39524_P050

Human Brain; WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml. Positive Control: Human brain; RXRB antibody - N-terminal region (ARP45637_P050) in Human Brain cells using Western Blot

ARP45637_P050

Hum. Adult Placenta; Host:Rabbit. Target Name:RXRB. Sample Tissue:Human Adult Placenta. Antibody Dilution: 1.0ug/ml.; RXRB antibody - N-terminal region (ARP45637_P050) in Hum. Adult Placenta cells using Western Blot

ARP45637_P050

Hum. Fetal Muscle; Host:Rabbit. Target Name:RXRB. Sample Tissue:Human Fetal Muscle. Antibody Dilution: 1.0ug/ml.; RXRB antibody - N-terminal region (ARP45637_P050) in Hum. Fetal Muscle cells using Western Blot

ARP45637_P050

Human Jurkat; WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate. RXRB is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; RXRB antibody - N-terminal region (ARP45638_P050) in Human Jurkat cells using Western Blot

ARP45638_P050

Human HEK293T; WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Transfected 293T. RXRB is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells.; RXRB antibody - N-terminal region (P100796_P050) in Human HEK293T cells using Western Blot

P100796_P050

Western blot analysis of RXRB Antibody (Center) Cat.-No AP53774PU-N in MDA-MB231 cell line lysates (35 µg/lane). RXRB (arrow) was detected using the purified Pab.

AP53774PU-N

TA302594 staining (1µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

TA302594

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. TA308585 diluted at 1:1000.

TA308585

Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RXR-Î² protein.

TA309231

WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Transfected 293TRXRB is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells

TA330072

WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml; Positive Control: Human brain

TA338001

Host: Rabbit; Target Name: RXRB; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0 ug/ml

TA338001

Host: Rabbit; Target Name: RXRB; Sample Tissue: Human Fetal Muscle; Antibody Dilution: 1.0 ug/ml

TA338001

WB Suggested Anti-RXRB Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate. RXRB is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

TA338002

Primary Antibodies

Catalog No.	Host	Iso.	Clone	Pres.	React.	Applications
TA302594	RXR-beta / RXRB antibody
	Goat Polyclonal Antibody against RXR beta
	Goat			Aff - Purified	Hu, Ms, Rt	WB	0.1 mg / €325.00
							OriGene Technologies, Inc.
TA308585	RXR-beta / RXRB antibody
	Rabbit polyclonal antibody to Retinoid X Receptor beta (retinoid X receptor, beta)
	Rabbit	IgG		Aff - Purified	Hu	WB	0.1 ml / €325.00
							OriGene Technologies, Inc.
TA309231	RXR-beta / RXRB (Hinge Region) antibody
	Mouse Anti-Retinoid X Receptor, b-Isotype Antibody
	Mouse	IgG1	147	Aff - Purified	Hu, Ms, Rt	WB	0.1 ml / €325.00
							OriGene Technologies, Inc.
TA330072	RXR-beta / RXRB antibody
	Rabbit Polyclonal Anti-RXRB Antibody
	Rabbit	IgG		Purified	Hu	WB	50 µg / €325.00
							OriGene Technologies, Inc.
TA338001	RXR-beta / RXRB antibody
	Rabbit Polyclonal Anti-RXRB Antibody
	Rabbit	IgG		Purified	Bov, Can, Eq, GP, Hu, Ms, Rb, Rt	WB	50 µg / €325.00
							OriGene Technologies, Inc.
+2 additional images
TA338002	RXR-beta / RXRB antibody
	Rabbit Polyclonal Anti-RXRB Antibody
	Rabbit	IgG		Purified	Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt	WB	50 µg / €325.00
							OriGene Technologies, Inc.
TA345349	RXR-beta / RXRB antibody
	Rabbit Polyclonal Anti-RXRB Antibody
	Rabbit	IgG		Purified	Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze	WB	50 µg / €325.00
							OriGene Technologies, Inc.
AP53774PU-N	RXR-beta / RXRB (Center) antibody
	Rabbit	Ig		Aff - Purified	Hu	WB	0.4 ml / €370.00
							Acris Antibodies GmbH

CRISPR

Catalog No.	Species	Donor Vector
KN200516	RXRB - human gene knockout kit via CRISPR
	Human	GFP-Puro	1 kit / €1,200.00
			OriGene Technologies, Inc.
KN200516BN	RXRB - human gene knockout kit via CRISPR
	Human	mBFP-Neo	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN200516LP	RXRB - human gene knockout kit via CRISPR
	Human	Luciferase-Puro	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN200516RB	RXRB - human gene knockout kit via CRISPR
	Human	RFP-BSD	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN315226	Rxrb - mouse gene knockout kit via CRISPR
	Mouse	GFP-Puro	1 kit / €1,200.00
			OriGene Technologies, Inc.
KN315226BN	Rxrb - mouse gene knockout kit via CRISPR
	Mouse	mBFP-Neo	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN315226LP	Rxrb - mouse gene knockout kit via CRISPR
	Mouse	Luciferase-Puro	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN315226RB	Rxrb - mouse gene knockout kit via CRISPR
	Mouse	RFP-BSD	1 kit / €1,290.00
			OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.
RC200516L2V	Lenti ORF particles, RXRB (mGFP-tagged) - Human retinoid X receptor, beta (RXRB), 200 uL, >10^7 TU/mL
		200 µl / €1,050.00
		OriGene Technologies, Inc.

RC200516L1V	Lenti ORF particles, RXRB (Myc-DDK tagged) - Human retinoid X receptor, beta (RXRB) , 200 uL, >10^7 TU/mL
		200 µl / €940.00
		OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.
MR208330L2V	Lenti ORF particles, Rxrb (GFP-tagged) - Mouse retinoid X receptor beta (Rxrb), transcript variant 2, 200 uL, >10^7 TU/mL
		200 µl / €1,150.00
		OriGene Technologies, Inc.

MR208330L1V	Lenti ORF particles, Rxrb (Myc-DDK-tagged) - Mouse retinoid X receptor beta (Rxrb), transcript variant 2, 200 uL, >10^7 TU/mL
		200 µl / €1,030.00
		OriGene Technologies, Inc.

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