S100A12 antibody

Principal name

S100A12 antibody

Alternative names for S100A12 antibody

S100-A12, Calgranulin-C, CAGC, CGRP, CAAF1, EN-RAGE, S100 calcium-binding protein A12, Calcium-binding protein in amniotic fluid 1, Extracellular newly identified RAGE-binding protein, Neutrophil S100 protein

SwissProt ID

O77791 (Rabit), P79105 (Bovin), P80310 (Pig), P80511 (Human)

Gene ID

6283 (S100A12)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of S100A12 antibody

S100 calcium binding protein A12, also known as S100A12, EN-RAGE, and calgranulin C, is a proinflammatory protein with significant potential as a biomarker. It is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. The member S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. It has been reported to be secreted by activated granulocytes and binds to the receptor for advanced gycation end products, which induces NfkappaB-dependent activation of endothelium (Foell et al., 2003). S100A12 is strongly expressed in inflamed synovial tissue typical in rheumatoid and psoriatic arthritis and may also prove an excellent biomarker for Inflammatory bowel disease (Kaiser et al., 2007). S100A12 protein may also be involved in chronic inflammation in atherosclerotic lesions including those of Type II diabetics (Kosaki et al. 2004) and the acceleration of atherosclerosis in hemodialysis patients (Mori et al., 2009).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

S100A12 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-S100A12 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502495) Mouse IgG1 OTI1D1 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

S100A12 antibody

Detection of S100A12 in HeLa whole cell extracts Rabbit IgG Purified Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

S100A12 antibody

Western blot analysis of extracts of various cell lines, using S100A12 antibody. Rabbit IgG Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

S100A12 antibody

ELISA: S100A12 Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

S100A12 antibody

S100A12 Mouse IgG1 19F5 Purified Hu C, E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

S100A12 antibody

S100A12 Mouse IgG2a 1F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

S100A12 antibody

S100A12 Mouse IgG2a 1F10 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

S100A12 antibody

Western blot analysis of S100A12 in HeLa whole cell extracts with S100A12 polyclonal antibody ( Cat# PAB12047 ). Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

S100A12 antibody

ELISA: S100A12 Antibody [43220002] Rabbit Hu E, WB
50 µg / €400.00
  Novus Biologicals Inc.

S100A12 antibody

S100A12 Rabbit Serum Hu WB
25 µl / €160.00
  Novus Biologicals Inc.

S100A12 antibody

Immunohistochemistry-Paraffin: S100A12 Antibody [NBP1-86694] - Immunohistochemical staining of human bone marrow shows strong nuclear positivity in bone marrow poietic cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

S100A12

S100A12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

S100A12

S100A12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

S100A12

S100A12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

S100A12

S100A12 Human 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

S100A12

S100A12 Human 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

S100A12 293T Cell Transient Overexpression Lysate(Denatured)

S100A12 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

S100A12 overexpression lysate

S100A12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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