Sacsin antibody

Principal name

Sacsin antibody

Alternative names for Sacsin antibody

SACS, KIAA0730, DnaJ homolog subfamily C member 29, DNAJC29

Gene ID

26278 (SACS)

Available reactivities

Hu (Human)

Available hosts


Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Sacsin antibody

This gene consists of nine exons including a gigantic exon spanning more than 12.8k bp. It encodes the sacsin protein, which includes a UBQ region at the N-terminus, a HEPN domain at the C-terminus and a DnaJ region upstream of the HEPN domain. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Sacsin antibody

Sacsin Rabbit IgG Purified Hu E, ICC/IF, P, WB
  OriGene Technologies, Inc.

Sacsin antibody

Sacsin Rabbit Hu E, P, WB
  Novus Biologicals Inc.

2 Item(s)

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