SAE2 / UBA2 antibody

Principal name

SAE2 / UBA2 antibody

Alternative names for SAE2 / UBA2 antibody

SUMO-activating enzyme subunit 2, UBLE1B, ARX, HRIHFB2115, Ubiquitin-like 1-activating enzyme E1B, Anthracycline-associated resistance ARX

SwissProt ID

P46946 (Yeast), Q7SXG4 (Danre), Q9UBT2 (Human), Q9Z1F9 (Mouse)

Gene ID

10054 (UBA2), 50995 (Uba2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey)

Available hosts

Rabbit, Goat, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of SAE2 / UBA2 antibody

Ubiquitin is covalently attached to target proteins by a multienzymatic system consisting of E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-ligating) enzymes. NEDD8, a ubiquitin-like protein, is conjugated to proteins in a manner analogous to ubiquitinylation. beta-amyloid precursor protein-binding protein-1 (APPBP1) can bind to NEDD8 in rabbit reticulocyte lysates. However, since APPBP1 shows similarity to only the N-terminal domain of an E1 enzyme, it must interact with a protein showing similarity to the C-terminal region of E1s. By searching sequence databases, a cDNAs encoding UBA3 was identified as the human homolog of yeast Uba3. The predicted 442-amino acid UBA3 protein shares 43% sequence identity with yeast Uba3. In vitro, UBA3 formed a complex with APPBP1 and a thioester linkage with NEDD8. APPBP1/UBA3 complex may function as an E1-like enzyme for the activation of NEDD8.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SAE2 / UBA2 antibody

  UBA2 mouse monoclonal antibody, clone OTI4A3 (formerly 4A3)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-UBA2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502504) Mouse IgG2a OTI4A3 Purified Can, Hu, Mky, Rt ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

SAE2 / UBA2 (N-term) antibody

SAE2 / UBA2 Goat Aff - Purified Hu, Ms E
0.1 mg / €350.00
  Acris Antibodies GmbH

SAE2 / UBA2 antibody

  Rabbit polyclonal anti-Uba2 antibody  
Western blot analysis of extracts from 293 cells, treated with UV (5mins), using Uba2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SAE2 / UBA2 (C-term) antibody

  Rabbit Polyclonal SAE2 Antibody  
Western blot analysis of SAE2 in 293 cell lysate with SAE2 antibody at 0.25 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAE2 / UBA2 antibody

  Rabbit Polyclonal Anti-Uba2 Antibody  
Western blot analysis on 293 cell lysate using Uba2 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAE2 / UBA2 antibody

Immunohistochemistry (IHC) analyzes of Uba2 antibody (Cat.-No.. AP06472PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SAE2 / UBA2 (160-210) antibody

Breast: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SAE2 / UBA2 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SAE2 / UBA2 (C-term) antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SAE2 / UBA2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Uba2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €230.00
  Assay Biotech

SAE2 / UBA2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Uba2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

UBA2 - human gene knockout kit via CRISPR

UBA2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

UBA2 - human gene knockout kit via CRISPR

UBA2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBA2 - human gene knockout kit via CRISPR

UBA2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBA2 - human gene knockout kit via CRISPR

UBA2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Uba2 - mouse gene knockout kit via CRISPR

Uba2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Uba2 - mouse gene knockout kit via CRISPR

Uba2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Uba2 - mouse gene knockout kit via CRISPR

Uba2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Uba2 - mouse gene knockout kit via CRISPR

Uba2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SAE2 / UBA2

  Recombinant protein of human ubiquitin-like modifier activating enzyme 2 (UBA2)  
SAE2 / UBA2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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