SAFB antibody

Principal name

SAFB antibody

Alternative names for SAFB antibody

Scaffold attachment factor B1, SAF-B1, SAFB1, SAF-B, HAP, HET, HSP27 estrogen response element-TATA box-binding protein

SwissProt ID

O88453 (Rat), Q15424 (Human)

Gene ID

6294 (SAFB), 64196 (Safb)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of SAFB antibody

This gene encodes a D-binding protein which has high specificity for scaffold or matrix attachment region D elements (S/MAR D). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.

2 Item(s)

per page

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SAFB (mGFP-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, SAFB (mGFP-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.

Lenti ORF particles, SAFB (Myc-DDK-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, SAFB (Myc-DDK-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €969.00
  OriGene Technologies, Inc.

2 Item(s)

per page
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