SAP102 / Dlg3 antibody

Principal name

SAP102 / Dlg3 antibody

Alternative names for SAP102 / Dlg3 antibody

SAP-102, Synapse-associated protein 102, Dlgh3, Disks large homolog 3, PSD-95/SAP90-related protein 1

SwissProt ID

P70175 (Mouse), Q62936 (Rat), Q92796 (Human)

Gene ID

1741 (DLG3), 58948 (Dlg3), 53310

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of SAP102 / Dlg3 antibody

SAP102 (also known as DLG3) is a PDZ containing domain protein that is also a member of the membrane-associated guanylate kise (MAGUK) family of multi-domain adaptor proteins. PDZ domains are conserved protein domains of about 90 amino acids involved in protein–protein recognition, protein targeting and assembly of multi-protein complexes. The me PDZ derives from the first three proteins in which these domains were identified: PSD-95 (a 95 kDa protein involved in sigling at the post-syptic density), DLG (the Drosophila melanogaster Discs Large protein) and ZO-1 (the zonula occludens 1 protein involved in maintence of epithelial polarity). MAGUKs are scaffolding proteins that comprise several modular protein binding motifs including one or more PDZ domains, a Src homology 3 (SH3) domain, and a catalytically ictive guanylate kise-like domain. The multidomain ture of PDZ-containing proteins ebles them to interact with multiple binding partners and hence organize larger sigling protein complexes. SAP102 has been shown to participate in the postsyptic density, a dedicated structure formed in postsyptic nerve termils that includes a specialized assembly of ion channels, receptors and sigling molecules that are involved in information processing and the modulation of syptic plasticity. Moreover, mutations in the SAP102 gene have been linked with a form of mental retardation.

General readings

Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SAP102 / Dlg3 antibody

  Mouse Monoclonal Anti-SAP102 Antibody  
Western blot analysis of SAP102 in rat brain extract using a dilution of 1:1000 of the antibody Mouse IgG1 S19-2 Purified Hu, Ms, Rt C, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

  Rabbit Polyclonal Anti-SAP 102  
Western blot analysis of rat brain membranes: 1. Anti-SAP 102 antibody, (1:400). 2. Anti-SAP 102 antibody, preincubated with the control fusion protein antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

  Rabbit Polyclonal Anti-DLG3 Antibody  
WB Suggested Anti-DLG3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate; DLG3 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

  Rabbit Polyclonal Anti-DLG3 Antibody  
WB Suggested Anti-DLG3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

  Rabbit Polyclonal Anti-DLG3 Antibody  
Host: Rabbit; Target Name: Dlg3; Sample Tissue: Mouse Lung lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

  DLG3 mouse monoclonal antibody, clone OTI3F2 (formerly 3F2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DLG3 (RC210860, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DLG3. Mouse IgG1 OTI3F2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SAP102 / Dlg3 antibody

  DLG3 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DLG3 (RC210860, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DLG3. Mouse IgG1 OTI5F1 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SAP102 / Dlg3 antibody

  Rabbit Polyclonal SAP102 Antibody  
ELISA: SAP102 Antibody - Affinity Purified Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N19/2 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

SAP102 / Dlg3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N19/2 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CRISPR

Catalog No. Species Donor Vector  

DLG3 - human gene knockout kit via CRISPR

DLG3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DLG3 - human gene knockout kit via CRISPR

DLG3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DLG3 - human gene knockout kit via CRISPR

DLG3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DLG3 - human gene knockout kit via CRISPR

DLG3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dlg3 - mouse gene knockout kit via CRISPR

Dlg3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dlg3 - mouse gene knockout kit via CRISPR

Dlg3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dlg3 - mouse gene knockout kit via CRISPR

Dlg3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dlg3 - mouse gene knockout kit via CRISPR

Dlg3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SAP102 / Dlg3 (transcript variant 1)

  Recombinant protein of human discs, large homolog 3 (Drosophila) (DLG3), transcript variant 1  
SAP102 / Dlg3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DLG3 (mGFP-tagged)-Human discs, large homolog 3 (Drosophila) (DLG3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DLG3 (mGFP-tagged)-Human discs, large homolog 3 (Drosophila) (DLG3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

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