SAP102 / Dlg3 antibody

Principal name

SAP102 / Dlg3 antibody

Alternative names for SAP102 / Dlg3 antibody

SAP-102, Synapse-associated protein 102, Dlgh3, Disks large homolog 3, PSD-95/SAP90-related protein 1

SwissProt ID

P70175 (Mouse), Q62936 (Rat), Q92796 (Human)

Gene ID

58948 (Dlg3), 1741 (DLG3)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ze (Zebrafish), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of SAP102 / Dlg3 antibody

SAP102 (also known as DLG3) is a PDZ containing domain protein that is also a member of the membrane-associated guanylate kise (MAGUK) family of multi-domain adaptor proteins. PDZ domains are conserved protein domains of about 90 amino acids involved in protein–protein recognition, protein targeting and assembly of multi-protein complexes. The me PDZ derives from the first three proteins in which these domains were identified: PSD-95 (a 95 kDa protein involved in sigling at the post-syptic density), DLG (the Drosophila melanogaster Discs Large protein) and ZO-1 (the zonula occludens 1 protein involved in maintence of epithelial polarity). MAGUKs are scaffolding proteins that comprise several modular protein binding motifs including one or more PDZ domains, a Src homology 3 (SH3) domain, and a catalytically ictive guanylate kise-like domain. The multidomain ture of PDZ-containing proteins ebles them to interact with multiple binding partners and hence organize larger sigling protein complexes. SAP102 has been shown to participate in the postsyptic density, a dedicated structure formed in postsyptic nerve termils that includes a specialized assembly of ion channels, receptors and sigling molecules that are involved in information processing and the modulation of syptic plasticity. Moreover, mutations in the SAP102 gene have been linked with a form of mental retardation.

General readings

Gomperts SN Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family. Cell 84:659-62 (1996). PubMed PMID: 8625403
Muller BM et al. SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo. Neuron 17:255-65 (1996). PubMed PMID: 8780649
Kornau HC et al. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269:1737-40 (1995). PubMed PMID: 7569905

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SAP102 / Dlg3 antibody

Western blot analysis of SAP102 in rat brain extract using a dilution of 1:1000 of the antibody Mouse IgG1 S19-2 Purified Hu, Ms, Rt C, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

Western blot analysis of rat brain membranes: 1. Anti-SAP 102 antibody, (1:400). 2. Anti-SAP 102 antibody, preincubated with the control fusion protein antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

WB Suggested Anti-DLG3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate; DLG3 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

WB Suggested Anti-DLG3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

Host: Rabbit; Target Name: Dlg3; Sample Tissue: Mouse Lung lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DLG3 (RC210860, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DLG3. Mouse IgG1 OTI3F2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SAP102 / Dlg3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DLG3 (RC210860, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DLG3. Mouse IgG1 OTI5F1 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SAP102 / Dlg3 antibody

ELISA: SAP102 Antibody - Affinity Purified Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAP102 / Dlg3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N19/2 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

SAP102 / Dlg3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N19/2 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

SAP102 / Dlg3 antibody

Western blot analysis of SAP102 in rat brain extract using a dilution of 1:1000 of the antibody Mouse IgG1 S19-2 Purified Hu, Ms, Rt C, IP, WB
25 µg / €190.00
  Acris Antibodies GmbH

SAP102 / Dlg3 antibody

SAP102 / Dlg3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SAP102 / Dlg3 antibody

SAP102 / Dlg3 Mouse Purified Hu, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

SAP102 / Dlg3 antibody

Western blot analysis of DLG3 over-expressed 293 cell line, cotransfected with DLG3 Validated Chimera RNAi ( Cat # H00001741-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with DLG3 monoclonal antibody (M03), clone 2B6 (Cat # H00001741-M03 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG2a 2B6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SAP102 / Dlg3 antibody

Human Heart; WB Suggested Anti-DLG3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; DLG3 antibody - N-terminal region (ARP43694_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Dros, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SAP102 / Dlg3 antibody

Human 293T; WB Suggested Anti-DLG3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate. DLG3 is supported by BioGPS gene expression data to be expressed in HEK293T.; DLG3 antibody - middle region (ARP43695_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SAP102 / Dlg3 (N-term) antibody

Rat Brain; WB Suggested Anti-Dlg3 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Rat Brain; Dlg3 antibody - N-terminal region (ARP43698_P050) in Rat Brain cells using Western Blot Rabbit Aff - Purified Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SAP102 / Dlg3 antibody

ELISA: SAP102 Antibody [26670002] - Affinity Purified Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

SAP102 / Dlg3 antibody

Western Blot: SAP102 Antibody [NB100-2063] - Figure 1 shows a Western blot of SAP102 on extract from COS cells transfected with rat SAP102 using NB100-2063. Rabbit Aff - Purified Rt C, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SAP102 / Dlg3 antibody

SAP102 / Dlg3 Mouse IgG1 S19-2 Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €410.00
  Novus Biologicals Inc.

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