SAP18 antibody

Principal name

SAP18 antibody

Alternative names for SAP18 antibody

2HOR0202, GIG38, Histone deacetylase complex subunit SAP18, Sin3-associated polypeptide 18 kDa, Sin3-associated polypeptide p18, Cell growth-inhibiting protein 38

SwissProt ID

O00422 (Human), O55128 (Mouse), Q3T022 (Bovin)

Gene ID

10284 (SAP18), 20220 (Sap18)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of SAP18 antibody

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.

General readings

Matyash A, et al. (2009) J Biol Chem. 284(5):3012-20.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SAP18 antibody

  Rabbit Polyclonal anti-SAP18 Antibody  
Host: Rabbit; Target Name: SAP18; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP18 antibody

  Rabbit Polyclonal Anti-SAP18 Antibody  
WB Suggested Anti-SAP18 Antibody Titration: 0.125 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAP18 (Center) antibody

Western blot analysis of SAP18 Antibody (Center) Cat.-No AP53795PU-N in K562 cell line lysates (35ug/lane).This demonstrates the SAP18 antibody detected the SAP18 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SAP18 - human gene knockout kit via CRISPR

SAP18 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SAP18 - human gene knockout kit via CRISPR

SAP18 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sap18 - mouse gene knockout kit via CRISPR

Sap18 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Sap18 - mouse gene knockout kit via CRISPR

Sap18 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sap18 - mouse gene knockout kit via CRISPR

Sap18 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sap18 - mouse gene knockout kit via CRISPR

Sap18 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SAP18

  Recombinant protein of human Sin3A-associated protein, 18kDa (SAP18)  
SAP18 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SAP18 (20-172, His-tag)

SAP18 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €990.00
  Acris Antibodies GmbH

SAP18 (20-172, His-tag)

SAP18 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SAP18 (mGFP-tagged) - Human Sin3A-associated protein, 18kDa (SAP18), 200 uL, >10^7 TU/mL

Lenti ORF particles, SAP18 (mGFP-tagged) - Human Sin3A-associated protein, 18kDa (SAP18), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SAP18 (Myc-DDK tagged) - Human Sin3A-associated protein, 18kDa (SAP18) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SAP18 (Myc-DDK tagged) - Human Sin3A-associated protein, 18kDa (SAP18) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Sap18 (GFP-tagged) - Mouse Sin3-associated polypeptide 18 (Sap18), 200 uL, >10^7 TU/mL

Lenti ORF particles, Sap18 (GFP-tagged) - Mouse Sin3-associated polypeptide 18 (Sap18), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Sap18 (Myc-DDK-tagged) - Mouse Sin3-associated polypeptide 18 (Sap18), 200 uL, >10^7 TU/mL

Lenti ORF particles, Sap18 (Myc-DDK-tagged) - Mouse Sin3-associated polypeptide 18 (Sap18), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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