SAR1B antibody

Principal name

SAR1B antibody

Alternative names for SAR1B antibody

SAR1B, SARA2, SARB, GTP-binding protein SAR1b, GTBPB

SwissProt ID

Q3T0T7 (Bovin), Q5HZY2 (Rat), Q5PYH3 (Pig), Q9CQC9 (Mouse), Q9Y6B6 (Human)

Gene ID

51128 (SAR1B), 66397 (Sar1b), 287276

Available reactivities

Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Por (Porcine), Ze (Zebrafish), African clawed frog

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of SAR1B antibody

SAR1B belongs to the small GTPase superfamily, SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus and is activated by the guanine nucleotide exchange factor PREB. SAR1B is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Defects in SAR1B are the cause of chylomicron retention disease (CMRD). CMRD is an autosomal recessive disorder of severe fat malabsorption associated with failure to thrive in infancy. The conditions are characterized by deficiency of fat-soluble vitamins, low blood cholesterol levels, and a selective absence of chylomicrons from blood. Affected individuals accumulate chylomicron-like particles in membrane-bound compartments of enterocytes, which contain large cytosolic lipid droplets.
Cellular localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.

General readings

Evans K, Burdge GC, Wootton SA, Collins JM, Clark ML, Tan GD, Karpe F, Frayn KN.
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia.
Atherosclerosis. 2007 Apr 25; [Epub ahead of print]
PMID: 17466309

Items 1 to 20 of 25 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SAR1B antibody

  Goat Polyclonal Antibody against SAR1B / SARA2  
TA302583 (0.03µg/ml) staining of Mouse Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAR1B antibody

  Rabbit polyclonal anti-SAR1B antibody  
Western blot analysis of extracts from LOVO cells and RAW264.7 cells, using SAR1B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SAR1B antibody

  Rabbit Polyclonal Anti-SAR1B Antibody  
WB Suggested Anti-SAR1B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAR1B (Center) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human skeletal muscle stained with SAR1B antibody (Center) Cat.-No AP53796PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SAR1B antibody

Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using SAR1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

SAR1B antibody

Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using SAR1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

SAR1B - human gene knockout kit via CRISPR

SAR1B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sar1b - mouse gene knockout kit via CRISPR

Sar1b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Sar1b - mouse gene knockout kit via CRISPR

Sar1b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sar1b - mouse gene knockout kit via CRISPR

Sar1b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sar1b - mouse gene knockout kit via CRISPR

Sar1b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SAR1B (transcript variant 2)

  Recombinant protein of human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 2  
SAR1B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SAR1B (transcript variant 1)

  Recombinant protein of human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 1  
SAR1B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SAR1B (1-198, His-tag)

SAR1B Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

SAR1B (1-198, His-tag)

SAR1B Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

SAR1B overexpression lysate

SAR1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SAR1B overexpression lysate

SAR1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SAR1B (mGFP-tagged) - Human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SAR1B (mGFP-tagged) - Human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SAR1B (mGFP-tagged) - Human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SAR1B (mGFP-tagged) - Human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SAR1B (Myc-DDK tagged) - Human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SAR1B (Myc-DDK tagged) - Human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Items 1 to 20 of 25 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn