SAR1B antibody

Principal name

SAR1B antibody

Alternative names for SAR1B antibody

SAR1B, SARA2, SARB, GTP-binding protein SAR1b, GTBPB

SwissProt ID

Q3T0T7 (Bovin), Q5HZY2 (Rat), Q5PYH3 (Pig), Q9CQC9 (Mouse), Q9Y6B6 (Human)

Gene ID

51128 (SAR1B)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of SAR1B antibody

SAR1B belongs to the small GTPase superfamily, SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus and is activated by the guanine nucleotide exchange factor PREB. SAR1B is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Defects in SAR1B are the cause of chylomicron retention disease (CMRD). CMRD is an autosomal recessive disorder of severe fat malabsorption associated with failure to thrive in infancy. The conditions are characterized by deficiency of fat-soluble vitamins, low blood cholesterol levels, and a selective absence of chylomicrons from blood. Affected individuals accumulate chylomicron-like particles in membrane-bound compartments of enterocytes, which contain large cytosolic lipid droplets.
Cellular localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.

General readings

Evans K, Burdge GC, Wootton SA, Collins JM, Clark ML, Tan GD, Karpe F, Frayn KN.
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia.
Atherosclerosis. 2007 Apr 25; [Epub ahead of print]
PMID: 17466309

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SAR1B antibody

TA302583 (0.03µg/ml) staining of Mouse Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SAR1B antibody

Western blot analysis of extracts from LOVO cells and RAW264.7 cells, using SAR1B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SAR1B antibody

WB Suggested Anti-SAR1B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SAR1B (Center) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human skeletal muscle stained with SAR1B antibody (Center) Cat.-No AP53796PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SAR1B antibody

293 overexpressing SAR1B and probed with SAR1B polyclonal antibody ( Cat # PAB7320 ) ( mock transfection in first lane), tested by Origene. Goat Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SAR1B antibody

Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using SAR1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

SAR1B antibody

Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using SAR1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

SAR1B antibody

Human Liver; WB Suggested Anti-SAR1B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Liver; SAR1B antibody - middle region (ARP56243_P050) in Human Liver cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SAR1B antibody

Western Blot: SAR1B / SARA2 Antibody [NBP1-06074] - HEK293 over expressing SAR1B (RC210593) and probed with NBP1-06074 (mock transfection in first lane), tested by Origene. Goat IgG Aff - Purified Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SAR1B antibody

Immunohistochemistry: SAR1B Antibody [NBP1-32725] - analysis of paraffin-embedded NCIN87 xenograft, using GTBPB antibody at 1:500 dilution. Rabbit IgG Hu, Ms ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

SAR1B antibody

SAR1B Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

SAR1B antibody

SAR1B Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SAR1B (transcript variant 2)

SAR1B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SAR1B (transcript variant 1)

SAR1B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SAR1B (1-198, His-tag)

SAR1B Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

SAR1B (1-198, His-tag)

SAR1B Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

SAR1B overexpression lysate

SAR1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SAR1B overexpression lysate

SAR1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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