Sarcalumenin (SRL) antibody

Principal name

Sarcalumenin (SRL) antibody

SwissProt ID

P13666 (Rabit), Q7TQ48 (Mouse), Q86TD4 (Human), Q90577 (Chick)

Gene ID

100009112 (SRL), 6345

Available reactivities

Can (Canine), GP (Guinea Pig), Ms (Mouse), Rb (Rabbit), Hu (Human)

Available hosts


Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)

Background of Sarcalumenin (SRL) antibody

Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner. The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin.
These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.

General readings

This product has been used in:Kutchai H & Campbell KP Calcium transport by sarcoplasmic reticulum of skeletal muscle is inhibited by antibodies against the 53-kilodalton glycoprotein of the sarcoplasmic reticulum membrane. Biochemistry 28:4830-9 (1989). PubMed PMID: 2527558
General / background references:Ohlendieck K et al. Analysis of excitation-contraction-coupling components in chronically stimulated canine skeletal muscle. Eur J Biochem 202:739-47 (1991). PubMed PMID: 1662614
Leberer E et al. Purification, calcium binding properties, and ultrastructural localization of the 53,000- and 160,000 (sarcalumenin)-dalton glycoproteins of the sarcoplasmic reticulum. J Biol Chem 265:10118-24 (1990). PubMed PMID: 2112542
Movsesian MA et al. Identification and characterization of proteins in sarcoplasmic reticulum from normal and failing human left ventricles. J Mol Cell Cardiol 22:1477-85 (1990). PubMed PMID: 2089160

3 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Sarcalumenin (SRL) antibody

Sarcalumenin (SRL) Mouse Hu WB
  Abnova Taiwan Corp.

Sarcalumenin (SRL) antibody

Sarcalumenin (SRL) Mouse IgG1 XIIC4 Ascites Can, GP, Ms, Rb ICC/IF, WB
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Sarcalumenin (SRL)

Sarcalumenin (SRL) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
  OriGene Technologies, Inc.

3 Item(s)

per page
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