Sarcolipin (SLN) antibody

Principal name

Sarcolipin (SLN) antibody

SwissProt ID

O00631 (Human), P42532 (Rabit), Q6SLE7 (Rat), Q9CQD6 (Mouse)

Gene ID

6588 (SLN)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Sarcolipin (SLN) antibody

Sarcolipin is a 31 amino acid integral membrane protein belonging to the sarcolipin family. The gene encoding for the protein maps to chromosome 11q22-q23. SLN, localizing to the sarcoplasmic reticulum, regulates Ca-ATPase activity in skeletal muscle. It associates with calcium ATPase SERCA1 (Sarco(endo)plasmic reticulum Ca2+-ATPases). In muscle tissue, SERCAs are regulated by sarcolipin and another membrane protein, phospholamban (PLN). SLN is expressed in high levels in fast-twitch muscle, which has high expression of SERCA1a, and in lower levels in cardiac muscle. In rats, however, expression of SLN is higher in cardiac muscle than in fast-twitch muscle.

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Lysates

Catalog No.    

SLN overexpression lysate

SLN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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