SARM1 antibody

Principal name

SARM1 antibody

Alternative names for SARM1 antibody

SARM, SAMD2, KIAA0524, Sterile alpha and TIR motif-containing protein 1, SAM domain-containing protein 2, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2

SwissProt ID

Q6IDD9 (Drome), Q6PDS3 (Mouse), Q6SZW1 (Human), Q86DA5 (Caeel)

Gene ID

23098 (SARM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of SARM1 antibody

SARM, also known as SAMD2, SARM1 or KIAA0524, is a 724 amino acid protein that localizes to the cytoplasm and contains one TIR domain and two sterile alpha motif (SAM) domains. Expressed predominately in liver and kidney and present at lower levels in placenta, SARM interacts with TICAM-1 and, via this interaction, blocks the transcriptional activation activity of TICAM-1 and functions as a negative regulator of Toll-like receptor signaling. Additionally, SARM is thought to be involved in innate immune responses and may also play a role in the negative regulation of NFⅹB activation. SARM exists as two alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 17.Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.

General readings

Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SARM1 (C-term) antibody

Western blot analysis of SARM in Daudi cell lysates with SARM antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SARM1 (N-term) antibody

Western blot analysis of SARM in Daudi cell lysate with SARM antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SARM1 antibody

Western Blot: SARM Antibody [TA337184] - Western blot analysis of SARM in A. Daudi cell lysate B. Daudi with blocking peptide. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SARM1 (93-292) antibody

Formalin-Fixed Paraffin-Embedded Human Brain, Cortex stained with SARM1 antibody Cat.-No. AM08374PU-N at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b Sarmy-1 Purified Hu IP, P
50 µg / €470.00
  Acris Antibodies GmbH

SARM1 (C-term) antibody

AP07256PU-N SARM1 antibody staining of Formalin-Fixed Paraffin-Embedded Human Tonsil at 2 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu, Ms ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SARM1 Control Peptide

SARM1
50 µg / €160.00
  Acris Antibodies GmbH

SARM1 (N-term) Control Peptide

SARM1
50 µg / €160.00
  Acris Antibodies GmbH

SARM1 antibody

SARM1 Rabbit Purified Hu, Ms ICC/IF, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

SARM1 antibody

Immunocytochemistry staining of Daudi cells using SARM1 polyclonal antibody ( Cat # PAB12917 ) at 2 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SARM1 antibody

SARM1 Rabbit Purified Hu, Ms P, WB
50 µg / €480.00
  Novus Biologicals Inc.

SARM1 antibody

SARM1 Mouse IgG2b Hu IP, P
50 µl / €480.00
  Novus Biologicals Inc.

SARM1 antibody

SARM1 Rabbit Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SARM1

SARM1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

13 Item(s)

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