SARS N antibody

Principal name

SARS N antibody

Alternative names for SARS N antibody

SARS-CoV N, Severe acute respiratory syndrome coronavirus Nucleoprotein, Nucleocapsid protein, Protein N, NC, 9a

SwissProt ID

P59595 (Cvhsa)

Gene ID


Available reactivities

Hu (Human), Vi (Virus), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)

Background of SARS N antibody

Generally, viruses have proteases to process their proteins into active form. Because of its pivotal role in the viral life cycle, proteases are primary targets for the development of antiviral agents. 3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CL protease is the only Coronavirus protein for which structural information is available. 3CL protease comprises three domains, the substrate-binding site is expected to be located between domains I and II, and domain III is a globular cluster comprising five helices. 3CL protease is a homodimer.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SARS N antibody

Western blot using Protein A Purified anti-SARS CoV Nucleocapsid (N) protein antibody shows detection of a 46-kDa band corresponding to the protein. Approx. 100 ng of protein was loaded for SDS-PAGE and transferred onto nitrocellulose. The blot was incubated with a 1:5,000 dilution of the antibody at room temperature for 1 h followed by detection using IRDye(TM)800 labeled Goat-a-Rabbit IgG [H&L] diluted 1:10,000. The fluorescence image was captured using the Odyssey(R) Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other  detection systems will yield similar results. Rabbit IgG Purified E, WB
0.5 mg / €520.00
  Acris Antibodies GmbH

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