SCAMP5 antibody

Principal name

SCAMP5 antibody

Alternative names for SCAMP5 antibody

Secretory carrier membrane protein 5, Secretory carrier-associated membrane protein 5

SwissProt ID

Q8TAC9 (Human), Q9JKD3 (Mouse), Q9JKE3 (Rat)

Gene ID

65171 (Scamp5), 56807, 192683 (SCAMP5)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB)

Background of SCAMP5 antibody

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

General readings

General / background references:Windoffer R et al. Tissue expression of the vesicle protein pantophysin. Cell Tissue Res 296:499-510 (1999). PubMed PMID: 10370136
Wu TT & Castle JD Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor. Mol Biol Cell 9:1661-74 (1998). PubMed PMID: 9658162
Singleton DR et al. Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions. J Cell Sci 110 Pt 17:2099-107 (1997). PubMed PMID: 9378760

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCAMP5 antibody

SCAMP5 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SCAMP5 (C-term) antibody

Mouse Liver; WB Suggested Anti-Scamp5 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Liver; Scamp5 antibody - C-terminal region (ARP59469_P050) in Mouse Liver cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

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