SCARB1 antibody

Principal name

SCARB1 antibody

Alternative names for SCARB1 antibody

SRB1, SR-BI, CLA1, CLA-1, CD36L1, Scavenger receptor class B member 1, CD36 antigen-like 1, CD36 and LIMPII analogous 1, Collagen type I receptor thrombospondin receptor-like 1

SwissProt ID

O18824 (Bovin), P97943 (Rat), Q61009 (Mouse), Q8SQC1 (Pig), Q8WTV0 (Human)

Gene ID

949 (SCARB1), 20778 (Scarb1), 25073

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Hst (Hamster), Mink, Bov (Bovine)

Available hosts

Rabbit, Goat, Mouse, Rat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Functional assay (FN), Neutralisation (NEUT), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of SCARB1 antibody

Scavenger receptors have been studied primarily for their ability to bind and internalize modified lipoproteins. They have been found in the development of atherosclerosis and other macrophage-associated functions. Scavenger receptors also function as pattern recognition receptors for a wide variety of pathogens. This finding indicates a potential role in host defense. SR-BI belongs together with CD36 to the class B scavenger receptor family.
SR-BI is a multiligand membrane protein existing in various organs such as the liver and various cell types such as endothelial cells, macrophages, brain cells, Leydig cells and Sertoli cells. SR-BI has been found as a receptor for phospholipids, free and (lipo)protein-bound ApoE, lipid-bound ApoA-I, HDL, hypochlorite-modified LDL and more. In liver, the PDZK-1 (and possible other PDZ domains) of SR-BI has been found to be essential for cell surface expression and, hence, reverse cholesterol transport. In the brain, the presence of SR-BI seems to be involved in the uptake of oxidatively modified lipoproteins and beta-amyloid protein complexed with ApoE, suggesting SR-BI to be an important tool for studies on neurodegenerative disorders. In the testis, SR-BI is expressed in two somatic cell types: Leydig cells and Sertoli cells. SR-BI functions at least partly as a phosphatidyl serine receptor (PSR), enabling Sertoli cells to recognize and phagocytose apoptotic spermatogenic cells at all stages of differentiation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCARB1 antibody

Detection of SR-BI in 25 ug of mouse liver lysate, using anti-SRBI at a 1:1,000 dilution, shows distinct band at 82 kDa. Rabbit Purified Hst, Hu, Mink, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-SCARB1 mouse monoclonal antibody. (TA507135) Mouse IgG1 OTI1F3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCARB1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-SCARB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA507181) Mouse IgG1 OTI1G4 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCARB1 antibody

Western blot analysis of SCARB1 in human spleen tissue lysate with SCARB1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB1 (238-250) antibody

TA329094 (0.03µg/ml) staining of Human Adrenal Gland lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB1 (C-term) antibody

TA329095 (0.01µg/ml) staining of Human Adrenal Gland lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Western blot analysis of extracts of various cell lines, using SCARB1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Western Blot: SR-BI Antibody [TA336639] - Detection of SR-BI in mouse liver lysate (20 ug) using NB 400-101. ECL detection 5 seconds. Rabbit Purified Bov, Hu, Ms, Rt C, F, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Western Blot: SR-BI Antibody [TA336641] - Detection of SR-BI  (80kDa) in mouse testis lysate total protein using TA336641. Rabbit Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Western Blot: SR-BI/SR-BII Antibody [TA336645] - Detection of RED-1 in 80 ug of total mouse liver lysates. Lane 1: wild-type mice, Lane 2: SR-BI deficient mice. Rabbit Purified Hu, Ms, Rt C, F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using (SCARB1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: 293T cells, PC3 cells, Primary antibody: (SCARB1 Antibody) at dilution 1/260, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB1 antibody

Human peripheral blood lymphocytes were stained with purified CLA (clone HECA-452) (filled histogram) or rat IgM isotype control (open histogram), followed by biotinylated anti-rat IgM and Sav-PE. Rat HECA-452 Purified Hu F, P
0.1 mg / €248.00
  OriGene Technologies, Inc.

SCARB1 antibody

Anti-SCARB1 mouse monoclonal antibody (TA507188) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SCARB1(RC210264). Mouse IgG2b OTI1E1 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCARB1 antibody

SCARB1 Mouse IgG1 SR-BI Purified Rt C, FN
0.1 mg / €540.00
  Acris Antibodies GmbH

SCARB1 antibody

SCARB1 Mouse IgG1 3D12 Liquid Rt C, NEUT
0.1 mg / €850.00
  Acris Antibodies GmbH

SCARB1 Control Peptide

SCARB1
50 µg / €160.00
  Acris Antibodies GmbH

SCARB1 antibody

Western blot analysis of Scarb1 in mouse liver lysate ( 20 µg ) with Scarb1 polyclonal antibody ( Cat# PAB12042 ). Rabbit Ms F, IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

SCARB1 antibody

Western blot analysis of Scarb1 in mouse liver lysate ( 20 µg ) with Scarb1 polyclonal antibody at 2 µg/ml ( Cat# PAB12043 ). Goat Ms ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

SCARB1 antibody

Western blot analysis of Scarb1/Scarb2 in 80 µg of total mouse liver lysates using Scarb1/Scarb2 polyclonal antibody ( Cat # PAB12123 ). Lane 1 : wild-type mice, Lane 2 : SR-BI deficient mice. Rabbit Ms C, ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

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