SCARB2 antibody

Principal name

SCARB2 antibody

Alternative names for SCARB2 antibody

LIMPII, LIMP II, LGP85, CD36L2, SRB2, SR-BII, LIMP2, Scavenger receptor class B member 2, Lysosome membrane protein 2, 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2

SwissProt ID

O35114 (Mouse), P27615 (Rat), Q14108 (Human), Q56660 (Vibch)

Gene ID

950 (SCARB2), 12492 (Scarb2), 117106

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Prim (Primate), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of SCARB2 antibody

Scavenger receptor class BI or SCARB1 gene belongs to CD36 receptor family and encodes for at least two mR splice variants which are SR-BI and SR-BII, among which SR-BII variant is the main isoform in terms of mR levels in certain tissues. For example, SR-BII mR is 48-fold higher than SR-BI in brain cells and protein levels reaching 10-15% of SR-BI in the liver. Similar differential SR-BII protein expression levels have also been detected in considerable amounts in other tissues, such as testes, retil pigment epithelial cells, and spleen. SR-BII isoform differs from SR-BI only in its entirely different, yet highly conserved, cytoplasmic C-terminus which has been proposed to contains a sigl responsible for marked alterations in cellular distribution as well as cellular trafficking of SR-BII compared with SR-BI. In contrast to SR-BI, SR-BII mediates the rapid uptake of significant amounts of HDL into endosomal recycling compartment by a pathway which is different from selective lipid uptake at the cell surface (mediated by SR-BI). Because SR-BII influence cellular cholesterol trafficking/homeostasis in a manner distinct from SR-BI, the relative expression as well as functiol activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCARB2 antibody

Human Prostate (formalin-fixed, paraffin-embedded) stained with SCARB2 antibody AP22677PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SCARB2 antibody

  Goat Anti-LIMP2 / SCARB2 Antibody  
TA305913 (0.1ug/ml) staining of Human Cerebral Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB2 antibody

  Rabbit Polyclonal LIMP2 Antibody  
Western blot analysis of LIMP2 in human skeletal muscle tissue lysate with LIMP2 antibody at 1 ug/ml in (A) the absence and (B) presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB2 (C-term) antibody

  Rabbit Polyclonal LIMP2 Antibody  
Western blot analysis of LIMP2 in human skeletal muscle tissue lysate with LIMP2 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCARB2 antibody

  Rabbit Polyclonal LIMPII/SR-B2 Antibody  
Western Blot: SR-BII Antibody [TA336640] - Western blot analysis of SR-BII in 1. Human heart lysate 2. Mouse heart lysate Rabbit Purified Bov, Hu, Ms, Rt C, F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCARB2 antibody

  Rabbit Polyclonal LIMPII/lpg85 Antibody  
Western Blot: LIMPII/lpg85 Antibody [TA336643] - Detection of LIMP II (~85 kDa) in Lane 1: Rat cardiac fibroblasts (RCF), 3T3 mouse fibroblasts (2), canine lung lysate (3), RCF treated with angiotensin II (4), and H2O2 (5), HEPG2 human liver lysate (6). Rabbit Purified Can, Hu, Ms, Prim, Rt C, ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

6 Item(s)

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