SCARB2 antibody

Principal name

SCARB2 antibody

Alternative names for SCARB2 antibody

LIMPII, LIMP II, LGP85, CD36L2, SRB2, SR-BII, LIMP2, Scavenger receptor class B member 2, Lysosome membrane protein 2, 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2

SwissProt ID

O35114 (Mouse), P27615 (Rat), Q14108 (Human), Q56660 (Vibch)

Gene ID

950 (SCARB2), 12492 (Scarb2), 117106

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Prim (Primate), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of SCARB2 antibody

Scavenger receptor class BI or SCARB1 gene belongs to CD36 receptor family and encodes for at least two mR splice variants which are SR-BI and SR-BII, among which SR-BII variant is the main isoform in terms of mR levels in certain tissues. For example, SR-BII mR is 48-fold higher than SR-BI in brain cells and protein levels reaching 10-15% of SR-BI in the liver. Similar differential SR-BII protein expression levels have also been detected in considerable amounts in other tissues, such as testes, retil pigment epithelial cells, and spleen. SR-BII isoform differs from SR-BI only in its entirely different, yet highly conserved, cytoplasmic C-terminus which has been proposed to contains a sigl responsible for marked alterations in cellular distribution as well as cellular trafficking of SR-BII compared with SR-BI. In contrast to SR-BI, SR-BII mediates the rapid uptake of significant amounts of HDL into endosomal recycling compartment by a pathway which is different from selective lipid uptake at the cell surface (mediated by SR-BI). Because SR-BII influence cellular cholesterol trafficking/homeostasis in a manner distinct from SR-BI, the relative expression as well as functiol activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.

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Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Scarb2 (GFP-tagged) - Mouse scavenger receptor class B, member 2 (Scarb2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Scarb2 (GFP-tagged) - Mouse scavenger receptor class B, member 2 (Scarb2), 200 uL, >10^7 TU/mL  
200 µl / €1,080.00
  OriGene Technologies, Inc.

Lenti ORF particles, Scarb2 (Myc-DDK-tagged) - Mouse scavenger receptor class B, member 2 (Scarb2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Scarb2 (Myc-DDK-tagged) - Mouse scavenger receptor class B, member 2 (Scarb2), 200 uL, >10^7 TU/mL  
200 µl / €970.00
  OriGene Technologies, Inc.

2 Item(s)

per page
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