Alternative names for SCARF1 antibody
KIAA0149, SREC, Endothelial cells scavenger receptor, Acetyl LDL receptor, Scavenger receptor class F member 1
Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of SCARF1 antibody
The protein recognised by this antibody is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.
Adachi H et al. Expression cloning of a novel scavenger receptor from human endothelial cells. J Biol Chem 272:31217-20 (1997). PubMed PMID: 9395444