SCD / SCD1 antibody

Principal name

SCD / SCD1 antibody

Alternative names for SCD / SCD1 antibody

Acyl-CoA desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase, Delta(9)-desaturase

SwissProt ID

O00767 (Human), O02858 (Pig), O62849 (Sheep), Q9BS07 (Human), Q9TT94 (Bovin)

Gene ID

6319 (SCD)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Can (Canine), Hst (Hamster), Por (Porcine), Prim (Primate), Bear, Rt (Rat), GP (Guinea Pig), Gt (Goat), Sh (Sheep)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SCD / SCD1 antibody

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681]; Wang et al., 2005).

General readings

1. Zhang S, Yang Y, Shi Y. Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells. Biochem J. 2004 Dec 20; [Epub ahead of print]
PMID: 15610069

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCD / SCD1 antibody

  Rabbit Polyclonal SCD Antibody  
Western Blot: SCD Antibody - Western blot on normal human liver. Rabbit Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCD / SCD1 antibody

  Mouse anti-SCD1 (Stearoyl-CoA desaturase) monoclonal antibody  
Western blot analysis of extracts from HepG2 cells, using DRD1 Antibody.The lane on the right is treated with the synthesized peptide. Mouse IgG CD.E10 Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCD / SCD1 antibody

  Rabbit polyclonal anti-SCD (stearoyl-CoA desaturase) antibody  
Western blot analysis of SCD with rat kidney tissue lysate. Rabbit Purified Hst, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCD / SCD1 antibody

  Rabbit Polyclonal Anti-SCD Antibody  
WB Suggested Anti-SCD Antibody Titration: 1.0ug/ml; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, GP, Gt, Hu, Ms, Rt, Sh P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCD / SCD1 antibody

  Rabbit Polyclonal Anti-SCD Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: 293T cells, lovo cells, Primary antibody: (SCD Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCD / SCD1 antibody

SCD / SCD1 Mouse IgG2b CD.E10 Aff - Purified Hu, Ms C, E, IP, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

SCD / SCD1 (C-term) antibody

AP22447PU-N SCD antibody staining of Paraffin Embedded Human Liver at 5 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu E, F, P
0.1 mg / €350.00
  Acris Antibodies GmbH

SCD / SCD1 (354-366) antibody

Immunohistochemistry Image: Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Can, Elephant, Hst, Hu, Ms, Por, Prim E, P
50 µg / €470.00
  Acris Antibodies GmbH

SCD / SCD1 antibody

SCD / SCD1 Mouse IgG2a 1B7 Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SCD / SCD1 antibody

SCD / SCD1 Mouse IgG2a 1B7 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

SCD / SCD1 antibody

Western blot analysis of SCD expression in 293 cells with SCD monoclonal antibody, clone CD.E10 ( Cat # MAB5546 ). Mouse IgG2b CD.E10 Hu, Ms C, E, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SCD / SCD1 antibody

SCD / SCD1 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

SCD / SCD1 antibody

Human Liver; SCD antibody - middle region (ARP32797_T100) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

SCD - human gene knockout kit via CRISPR

SCD - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SCD - human gene knockout kit via CRISPR

SCD - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCD - human gene knockout kit via CRISPR

SCD - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCD - human gene knockout kit via CRISPR

SCD - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCD / SCD1

SCD / SCD1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

SCD / SCD1

SCD / SCD1 Human
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SCD overexpression lysate

SCD overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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