SCN11A / PN5 antibody

Principal name

SCN11A / PN5 antibody

Alternative names for SCN11A / PN5 antibody

SCN12A, SNS2, NaN, Sodium channel protein type 11 subunit alpha, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5

SwissProt ID

O88457 (Rat), Q9R053 (Mouse), Q9UI33 (Human)

Gene ID

11280 (SCN11A), 29701 (Scn11a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of SCN11A / PN5 antibody

Voltage-gated + channels (V) are essential for the generation of action potentials and for cell excitability. V channels are activated in response to depolarization and selectively allow flow of + ions. To date, nine V α subunits have been cloned and med V1.1-1.9. Expression of the α subunit is developmentally and tissue specific. The V channels are classified into two groups according to their sensitivity to tetrodotoxin (TTX): TTX-sensitive and TTX-resistant channels. TTX-resistant channels have been suggested to play an important role in nociceptive transmission. Two TTX-resistant V channels are expressed in dorsal root ganglion (DRG) neurons, V1.8 and V1.9. The V1.9 channel (also called N or SNS2) is preferentially expressed in small-diameter DRG neurons. Recently, it was shown that BDNF activates v1.9 channels in the hippocampus suggesting that its expression is not restricted to DRG alone.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN11A / PN5 antibody

  Anti-SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm,Nucleus. Positive control: Human cervical and lung cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN11A / PN5 antibody

  Anti-SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm,Nucleus. Positive control: Human cervical and esophagus cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN11A / PN5 antibody

  Anti-SCN11A Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm;cell membrane. Positive control: Human esophagus and breast cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using SCN11A antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN11A / PN5 antibody

  Anti-SCN11A Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human breast and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using SCN11A antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN11A / PN5 antibody

  Rabbit polyclonal Anti-NaV1.9  
Western blot analysis of rat DRG lysates: 1. Anti-Nav1.9 antibody , (1:200). 2. Anti-Nav1.9 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN11A / PN5 antibody

SCN11A / PN5 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SCN11A - human gene knockout kit via CRISPR

SCN11A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SCN11A - human gene knockout kit via CRISPR

SCN11A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN11A - human gene knockout kit via CRISPR

SCN11A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN11A - human gene knockout kit via CRISPR

SCN11A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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