SCN1A antibody

Principal name

SCN1A antibody

Alternative names for SCN1A antibody

NAC1, SCN1, Sodium channel protein type 1 subunit alpha, Sodium channel protein type I subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.1, Sodium channel protein brain I subunit alpha

SwissProt ID

P04774 (Rat), P35498 (Human)

Gene ID

81574 (Scn1a), 6323 (SCN1A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of SCN1A antibody

Voltage-gated sodium channels (v) are essential for the generation of action potentials and for cell excitability. v channels are activated in response to depolarization and selectively allow flow of + ions. To date, nine v a subunits have been cloned and med v1.1-v1.9. The v channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive (v1.1, v1.2, v1.3, v1.4, v1.6 and v1.7) and TTX-resistant (v1.5, v1.8 and v1.9). Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. The expression of the α subunit isoform is developmentally regulated and tissue specific. + channels in the adult central nervous system and heart contain β1 through β4 subunits, whereas + channels in adult skeletal muscle have only the β1 subunit. v1.1 is a highly tetrodotoxin-sensitive channel and is broadly expressed in neurons. Mutations in V1.1 are associated with at least two forms of epilepsy. Gain-of-function missense mutations are a primary cause of generalized epilepsy with febrile seizures plus (GEFS+). Loss-of-function mutations cause severe myoclonic epilepsy of infancy (SMEI).

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Nav1.1 antibody

Immunohistochemical analysis of Nav1.1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Nav1.1 antibody

Immunohistochemical analysis of Nav1.1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Nav1.1 antibody

Immunohistochemical analysis of Nav1.1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

SCN1A antibody

  Mouse Monoclonal Anti-Nav1.1 Antibody  
IHC analysis of Nav1.1 in frozen sections of mouse brain extract using the antibody Mouse IgG1 S74-71 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCN1A antibody

  Rabbit polyclonal Anti-NaV1.1  
Western blot analysis of rat brain membranes: 1. Anti-Nav1.1 antibody , (1:200). 2. Anti-Nav1.1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN1A antibody

  Rabbit polyclonal Anti-Pan NaV  
Western blot analysis of rat brain membranes: 1. Anti-Pan Nav antibody , (1:200). 2. Anti-Pan Nav antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN1A antibody

  Rabbit Polyclonal Anti-SCN1A Antibody (N-Terminus)  
Anti-SCN1A / Nav1.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Ze
50 µg / €379.00
  OriGene Technologies, Inc.

SCN1A antibody

  Rabbit Polyclonal Anti-Sodium Channel-pan Antibody  
Western blot analysis on HuvEc cell lysate using Sodium Channel-pan Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCN1A antibody

  Rabbit Polyclonal anti-Sodium Channel-pan Antibody  
Human Brain stained with anti-Sodium Channel-pan antibody. Rabbit Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN1A antibody

Whole brain immunohistochemistry Mouse IgG1 K74/71 Supernatant Hu, Ms, Rt C, ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

SCN1A antibody

Whole brain immunohistochemistry Mouse IgG1 K74/71 Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

SCN1A antibody

Pancreas stained in IHC-P with SCN1A antibody Rabbit Purified Hu, Ms, Rt C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

SCN1A antibody

Immunohistochemical staining of Scn1a on formalin fixed, paraffin embedded human cerebellum with Scn1a polyclonal antibody. Rabbit Hu P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

SCN1A antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Sodium Channel-pan Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

SCN1A antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Sodium Channel-pan Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

SCN1A - human gene knockout kit via CRISPR

SCN1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SCN1A - human gene knockout kit via CRISPR

SCN1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN1A - human gene knockout kit via CRISPR

SCN1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN1A - human gene knockout kit via CRISPR

SCN1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SCN1A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type I, alpha subunit (SCN1A), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN1A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type I, alpha subunit (SCN1A), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

20 Item(s)

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