SCN1B antibody

Principal name

SCN1B antibody

Alternative names for SCN1B antibody

Sodium channel subunit beta-1

SwissProt ID

P53788 (Rabit), P97952 (Mouse), Q00954 (Rat), Q07699 (Human), Q17QN4 (Bovin), Q4PPC4 (Canfa)

Gene ID

6324 (SCN1B), 29686 (Scn1b)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of SCN1B antibody

Voltage-gated sodium channels (v) are essential for the generation of action potentials and for cell excitability. To date, nine v α subunits have been cloned and med v1.1-v1.9.2,3 Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β-subunits (v β-subunit). The v β-subunit gene family consists of four members: β1 (SCN1B), β2 (SCN2B), β3 (SCN3B), and β4 (SCN4B) having type I topology, containing an extracellular amino-terminus, a single transmembrane segment, and an intracellular carboxyl-terminus.They modulate channel gating, assembly, and cell surface expression in heterologous cell systems. vβ-subunits are cell adhesion molecules of the Ig superfamily, which interact with extracellular matrix, transmembrane sigling, and cell adhesion molecules. In the adult central nervous system and heart, sodium channels are associate with β1- β4 subunits, whereas in adult skeletal muscle they are associate only with the β1 subunit. This association appears to be a late event in sodium channel biosynthesis.

General readings

Selmer,K.K., (2008) Acta Neurol. Scand. 117 (4), 289-292

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN1B antibody

Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and rat skeletal muscle (lanes 3 and 6): 1-3. Anti-NaVß1 (extracellular) antibody , (1:400). 4-6. Anti-NaVß1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN1B antibody

WB Suggested Anti-SCN1B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN1B antibody

WB Suggested Anti-Scn1b Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN1B (N-term) antibody

Western blot with SCN1B Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

SCN1B (N-term) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SCN1B Antibody (N-term) Cat.-No AP53815PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SCN1B Antibody (N-Term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SCN1B antibody

Western blot analysis of cell and tissue lysates with SCN1B polyclonal antibody ( Cat # PAB13688 ).
Lane 1 : Rat brain tissue.
Lane 2 : Rat testicular tissue.
Lane 3 : MCF-7.
Lane 4 : HeLa.
Lane 5 : MM231.
Lane 6 : HT-1080. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SCN1B antibody

Human HeLa; WB Suggested Anti-SCN1B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Hela cell lysate; SCN1B antibody - middle region (ARP35028_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SCN1B antibody

SCN1B Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

SCN1B antibody

SCN1B Rabbit IgG Hu, Ms, Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCN1B

SCN1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SCN1B

SCN1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SCN1B overexpression lysate

SCN1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SCN1B overexpression lysate

SCN1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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