SCN1B antibody

Principal name

SCN1B antibody

Alternative names for SCN1B antibody

Sodium channel subunit beta-1

SwissProt ID

P53788 (Rabit), P97952 (Mouse), Q00954 (Rat), Q07699 (Human), Q17QN4 (Bovin), Q4PPC4 (Canfa)

Gene ID

6324 (SCN1B), 29686 (Scn1b), 20266

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of SCN1B antibody

Voltage-gated sodium channels (v) are essential for the generation of action potentials and for cell excitability. To date, nine v α subunits have been cloned and med v1.1-v1.9.2,3 Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β-subunits (v β-subunit). The v β-subunit gene family consists of four members: β1 (SCN1B), β2 (SCN2B), β3 (SCN3B), and β4 (SCN4B) having type I topology, containing an extracellular amino-terminus, a single transmembrane segment, and an intracellular carboxyl-terminus.They modulate channel gating, assembly, and cell surface expression in heterologous cell systems. vβ-subunits are cell adhesion molecules of the Ig superfamily, which interact with extracellular matrix, transmembrane sigling, and cell adhesion molecules. In the adult central nervous system and heart, sodium channels are associate with β1- β4 subunits, whereas in adult skeletal muscle they are associate only with the β1 subunit. This association appears to be a late event in sodium channel biosynthesis.

General readings

Selmer,K.K., (2008) Acta Neurol. Scand. 117 (4), 289-292

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN1B antibody

  Rabbit polyclonal Anti-NaVBeta1 (extracellular)  
Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and rat skeletal muscle (lanes 3 and 6): 1-3. Anti-NaVß1 (extracellular) antibody , (1:400). 4-6. Anti-NaVß1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN1B antibody

  Rabbit Polyclonal Anti-SCN1B Antibody  
WB Suggested Anti-SCN1B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN1B antibody

  Rabbit Polyclonal Anti-Scn1b Antibody  
WB Suggested Anti-Scn1b Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN1B antibody

  Rabbit Polyclonal Anti-SCN1B Antibody  
SCN1B Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN1B (N-term) antibody

Western blot with SCN1B Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

SCN1B (N-term) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SCN1B Antibody (N-term) Cat.-No AP53815PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SCN1B Antibody (N-Term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SCN1B - human gene knockout kit via CRISPR

SCN1B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SCN1B - human gene knockout kit via CRISPR

SCN1B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN1B - human gene knockout kit via CRISPR

SCN1B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN1B - human gene knockout kit via CRISPR

SCN1B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Scn1b - mouse gene knockout kit via CRISPR

Scn1b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Scn1b - mouse gene knockout kit via CRISPR

Scn1b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Scn1b - mouse gene knockout kit via CRISPR

Scn1b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Scn1b - mouse gene knockout kit via CRISPR

Scn1b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SCN1B overexpression lysate

SCN1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SCN1B overexpression lysate

SCN1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SCN1B (mGFP-tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant a, 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN1B (mGFP-tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant a, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SCN1B (mGFP-tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant b, 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN1B (mGFP-tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant b, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, SCN1B (Myc-DDK tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant a , 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN1B (Myc-DDK tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant a , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, SCN1B (Myc-DDK tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant b , 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN1B (Myc-DDK tagged) - Human sodium channel, voltage-gated, type I, beta (SCN1B), transcript variant b , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn