SCN3A antibody

Principal name

SCN3A antibody

Alternative names for SCN3A antibody

NAC3, KIAA1356, Sodium channel protein type 3 subunit alpha, Sodium channel protein type III subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.3, Sodium channel protein brain III subunit alpha, Voltage-gated sodium channel subtype III

SwissProt ID

P08104 (Rat), Q9NY46 (Human), Q9Y6P4 (Human)

Gene ID

6328 (SCN3A), 497770 (Scn3a)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of SCN3A antibody

Voltage-gated sodium channels (v) are essential for the generation of action potentials and for cell excitability. v channels are activated in response to depolarization and selectively allow flow of + ions. To date, nine v α subunits have been cloned and med v1.1-v1.9.4-5 The v channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive (v1.1, v1.2, v1.3, v1.4, v1.6 and v1.7) and TTX-resistant (v1.5, v1.8 and v1.9). Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. The expression of the α subunit isoform is developmentally regulated and tissue specific. Sodium channels in the adult central nervous system and heart contain β1 through β4 subunits, whereas sodium channels in adult skeletal muscle have only the β1 subunit. v1.3 is highly expressed in embryonic sensory neurons and CNS, but its level dramatically decreases in adult rodents. Up-regulation of v1.3 channel expression was described in injured neurons and injured spil cord.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN3A antibody

  SCN3A / Nav1.3 Rabbit Polyclonal (Internal) Antibody  
Anti-SCN3A / Nav1.3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

SCN3A antibody

  Rabbit polyclonal Anti-NaV1.3  
Western blot analysis of rat newborn brain membranes: 1. Anti-Nav1.3 antibody , (1:200). 2. Anti-Nav1.3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN3A antibody

SCN3A Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SCN3A - human gene knockout kit via CRISPR

SCN3A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SCN3A - human gene knockout kit via CRISPR

SCN3A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN3A - human gene knockout kit via CRISPR

SCN3A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCN3A - human gene knockout kit via CRISPR

SCN3A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SCN3A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN3A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

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