SCN3A antibody

Principal name

SCN3A antibody

Alternative names for SCN3A antibody

NAC3, KIAA1356, Sodium channel protein type 3 subunit alpha, Sodium channel protein type III subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.3, Sodium channel protein brain III subunit alpha, Voltage-gated sodium channel subtype III

SwissProt ID

P08104 (Rat), Q9NY46 (Human), Q9Y6P4 (Human)

Gene ID

6328 (SCN3A), 497770 (Scn3a)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of SCN3A antibody

Voltage-gated sodium channels (v) are essential for the generation of action potentials and for cell excitability. v channels are activated in response to depolarization and selectively allow flow of + ions. To date, nine v α subunits have been cloned and med v1.1-v1.9.4-5 The v channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive (v1.1, v1.2, v1.3, v1.4, v1.6 and v1.7) and TTX-resistant (v1.5, v1.8 and v1.9). Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. The expression of the α subunit isoform is developmentally regulated and tissue specific. Sodium channels in the adult central nervous system and heart contain β1 through β4 subunits, whereas sodium channels in adult skeletal muscle have only the β1 subunit. v1.3 is highly expressed in embryonic sensory neurons and CNS, but its level dramatically decreases in adult rodents. Up-regulation of v1.3 channel expression was described in injured neurons and injured spil cord.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN3A antibody

Anti-SCN3A / Nav1.3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky
50 µg / €345.00
  OriGene Technologies, Inc.

SCN3A antibody

Western blot analysis of rat newborn brain membranes: 1. Anti-Nav1.3 antibody , (1:200). 2. Anti-Nav1.3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN3A antibody

SCN3A Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

SCN3A antibody

Detection limit for recombinant GST tagged SCN3A is approximately 0.3ng/ml as a capture antibody. Mouse IgG2b 3F3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SCN3A antibody

SCN3A Mouse IgG2a 2F8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SCN3A antibody

Immunohistochemistry-Paraffin: SCN3A Antibody [NBP1-82597] Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCN3A

SCN3A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SCN3A

SCN3A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

8 Item(s)

per page
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