SCN4B antibody

Principal name

SCN4B antibody

Alternative names for SCN4B antibody

Sodium channel subunit beta-4

SwissProt ID

Q08E08 (Bovin), Q7M729 (Mouse), Q7M730 (Rat), Q8IWT1 (Human)

Gene ID

6330 (SCN4B), 315611 (Scn4b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SCN4B antibody

Voltage-gated sodium channels (V) are essential for the generation of action potentials and for cell excitability. V channels are activated in response to depolarization and selectively allow flow of + ions. To date, nine V α subunits have been cloned and med v1.1-v1.9. The v channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive (V1.1, V1.2, V1.3, V1.4, V1.6 and V1.7) and TTX-resistant (V1.5, V1.8 and V1.9). Mammalian + channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. The expression of the α subunit isoform is developmentally regulated and tissue specific. + channels in the adult central nervous system and heart contain β1 through β4 subunits, whereas + channels in adult skeletal muscle have only the β1 subunit. vβ4 has been associated with Long QT syndrome and with Huntington's disease, showing a distinct down regulation of Vβ4 in the presymptomatic stage of HD mice, whereas other voltage-gated ion channel subunits were later decreased.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN4B antibody

Western blot analysis of extracts from HepG2 cells and Jurkat cells, using SCN4B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN4B antibody

Western blot analysis of  rat brain (lanes 1 and 5), rat cortex (lane 2 and 6), mouse brain (lanes 3 and 7) and SH-SY5Y (lanes 4 and 8) lysates: 1-4. Anti-Navß4 (extracellular) antibody , (1:800). 5-8. Anti-Navß4 (extracellular) antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN4B antibody

Adult rat sciatic nerve immuno-fluorescence staining: paranodes labeled with Caspr (green) surround nodes of Ranvier labeled with Beta-IV spectrin (blue) and N168/6 (red). Images courtesy of Shelly Buffington and Matt Rasband (Baylor College of Medicine). Mouse IgG1 N168/6 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

SCN4B antibody

Adult rat brain immunohistochemistry. N168/6 staining in striatal efferents in globus pallidus (left) and of Purkinje cell bodies and dendrites in cerebellar cortex (right). Mouse IgG1 N168/6 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

SCN4B antibody

Western blot analysis of extracts from HepG2/Jurkat cells, using SCN4B Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

SCN4B antibody

Western blot analysis of extracts from HepG2/Jurkat cells, using SCN4B Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

SCN4B antibody

SCN4B Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

SCN4B antibody

SCN4B Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

SCN4B antibody

Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057] - Immunohistochemical staining of human small intestine shows moderate positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCN4B (transcript variant 1)

SCN4B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

10 Item(s)

per page
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