SCN5A antibody

Principal name

SCN5A antibody

Alternative names for SCN5A antibody

HB1, HB2, HH1, HBBD, CDCD2, Nav1.5, LQT3, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5, Sodium channel protein cardiac muscle subunit alpha

SwissProt ID

P15389 (Rat), Q14524 (Human)

Gene ID

6331 (SCN5A), 25665 (Scn5a)

Available reactivities

Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Fi (Fish), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Op (Opossum), Por (Porcine), Prim (Primate), Rt (Rat), Tr (Turkey), Bear, Rb (Rabbit), Ze (Zebrafish), GP (Guinea Pig)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SCN5A antibody

Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signalling in nerves and muscles. They have also been detected in lymphocytes, glia, and fibroblasts. VGSC proteins are comprised of a core alpha-subunit, together with one or more additional regulatoy beta-subunit. VCSC expression has been detected in a number of tumour cell lines and has been implicated in the metastatic behaviour of breast and prostate cancer cells. Na(v)1.5, the major cardiac voltage-gated Na(+) channel, plays a central role in the generation of the cardiac action potential and in the propagation of electrical impulses in the heart. Its importance for normal heart function has been recently exemplified by reports of numerous mutations found in the gene SCN5A which encodes Na(v)1.5.

General readings

Shah,V.N., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (10), 3592-3597

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN5A antibody

Western blot analysis of extracts from HuvEc cells, using Sodium Channel-pan Antibody (#TA314511).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN5A antibody

Predicted cell location: Cytoplasm. Positive control: Human breast and ovarian cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using SCN5A antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN5A antibody

Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SCN5A antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SCN5A antibody

Western blot analysis of Nav1.5 in human-Nav1.5 transfected HEK-293 cells: 1. Anti-Human-Nav1.5 antibody, (1:200). 2. Anti-Human-Nav1.5 antibody, preincubated with the control peptide antigen Rabbit Purified Hu, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN5A antibody

Western blot analysis of rat heart membranes: 1. Anti-Nav1.5 antibody , (1:200). 2. Anti-Nav1.5 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SCN5A antibody

WB Suggested Anti-SCN5A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN5A antibody

WB Suggested Anti-SCN5A Antibody Titration: HEK cel lysate; HEK cel with HuNav1.5 transfected lysate; Mouse Heart lysate 80 ug protein on gelQC Antibodies 1:100 in PBS/Tweensecondary antibodie 1:10.000 ( IRDYE 800 CWGoat anti Rabbit IgG) analyse with the Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN5A antibody

WB Suggested Anti-SCN5A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: SW620 cell lysate SCN5A is supported by BioGPS gene expression data to be expressed in SW620 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCN5A antibody

Anti-SCN5A / Nav1.5 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

SCN5A antibody

Two colour Immunocytochemistry on Nav1.5 overexpressing 293 cells (150uL per slide): A. Anti-nNav 1.5 [4G8:1G7], B. DAPI Mouse IgG1 4G8:1G7 Purified Hu F, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCN5A (Internal) antibody

Figure 1. Staining SCN5A in Brain, Cortex by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Por, Prim, Rt, Slime Mold, Tr E, P
50 µg / €470.00
  Acris Antibodies GmbH

SCN5A antibody

SCN5A Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

SCN5A antibody

SCN5A Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

SCN5A antibody

Hum. Fetal Muscle; Host: Rabbit. Target Name: SCN5A. Sample Tissue: Human Fetal Muscle. Antibody Dilution: 1.0ug/ml.; SCN5A antibody - N-terminal region (ARP34934_P050) in Hum. Fetal Muscle cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SCN5A antibody

MCF7 Whole Cell; Host: Rabbit. Target Name:SCN5A. Sample Tissue:MCF7 Whole Cell. Lane A: Primary Antibody . Lane B:Primary Antibody + Blocking Peptide . Primary Antibody Concentration:1ug/ml. Peptide Concentration: 5ug/ml. Lysate Quantity: 25ug/lane/Lane. Gel Concentration: 0.12.; SCN5A antibody - C-terminal region (ARP35542_P050) in MCF7 Whole Cell cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rb, Rt, Ze P, WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCN5A

SCN5A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SCN5A

SCN5A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SCN5A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SCN5A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

18 Item(s)

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