SCO1 / SCOD1 antibody

Principal name

SCO1 / SCOD1 antibody

Alternative names for SCO1 / SCOD1 antibody

Protein SCO1 homolog mitochondrial

SwissProt ID

A1A4J8 (Bovin), O42899 (Schpo), O75880 (Human), P23833 (Yeast), Q5SUC9 (Mouse)

Gene ID

6341 (SCO1), 52892 (Sco1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of SCO1 / SCOD1 antibody

Synthesis of cytochrome c oxidase 1 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO1 and SCO2 are dependent on copper ion binding. Mutations in either gene can lead to cytochrome c oxidase respiratory chain defects, with a missense mutation in human SCO1 (P174L) associated with a fatal neonatal hepatopathy when the second allele is also non-functional, suggesting the pathology is due to loss of function. It has been suggested that this mutation alters the SCO1 affinity for the copper (I) ion, thus impairing the efficiency of copper transfer to the cytochrome c oxidase. At least two isoforms of SCO1 are known to exist and both are recognized by the SCO1 antibody. This SCO1 antibody has no cross-reactivity to SCO2.

General readings

Petruzzella V., et al. (1999) Genomics. 54 (3): 494–504.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCO1 / SCOD1 antibody

Immunofluorescence of purified MaxPab antibody to SCO1 on HepG2 cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

SCO1 / SCOD1 antibody

Immunofluorescence of purified MaxPab antibody to SCO1 on HepG2 cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SCO1 / SCOD1 antibody

Western blot analysis of SCO1 in human brain tissue lysate with SCO1 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCO1 / SCOD1 antibody

WB Suggested Anti-SCO1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human heart Rabbit IgG Purified Bov, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCO1 / SCOD1 antibody

Figure 2. Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) using SCO1 antibody Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SCO1 / SCOD1 Control Peptide

SCO1 / SCOD1
50 µg / €160.00
  Acris Antibodies GmbH

SCO1 / SCOD1 antibody

SCO1 / SCOD1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SCO1 / SCOD1 antibody

Immunohistochemistry of SCO1 in human brain tissue with SCO1 polyclonal antibody ( Cat # PAB12983 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SCO1 / SCOD1 antibody

Human Heart; WB Suggested Anti-SCO1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human heart; SCO1 antibody - middle region (ARP56592_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SCO1 / SCOD1 antibody

SCO1 / SCOD1 Rabbit Hu, Ms, Rt P, WB
50 µg / €480.00
  Novus Biologicals Inc.

SCO1 / SCOD1 antibody

Immunohistochemistry-Paraffin: SCO1 Antibody [NBP1-77273] - Human brain tissue with SCO1 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

SCO1 / SCOD1 antibody

Immunohistochemistry-Paraffin: SCO1 Antibody [NBP1-87073] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

SCO1 / SCOD1 antibody

Immunohistochemistry-Paraffin: SCO1 Antibody [NBP1-87074] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCO1 / SCOD1

SCO1 / SCOD1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SCO1 / SCOD1

SCO1 / SCOD1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

SCO1 / SCOD1 (132-301, His-tag)

SCO1 / SCOD1 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

SCO1 / SCOD1 (132-301, His-tag)

SCO1 / SCOD1 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

SCO1 / SCOD1

SCO1 / SCOD1 Human
2 µg / €300.00
  Abnova Taiwan Corp.

SCO1 / SCOD1

SCO1 / SCOD1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SCO1 / SCOD1

SCO1 / SCOD1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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