SCP2 / SCPX antibody

Principal name

SCP2 / SCPX antibody

Alternative names for SCP2 / SCPX antibody

SCP-2, SCP-X, SCP-chi, Sterol carrier protein 2, Sterol carrier protein X, NSL-TP, Non-specific lipid-transfer protein, Propanoyl-CoA C-acyltransferase

SwissProt ID

O62742 (Rabit), P07857 (Bovin), P11915 (Rat), P22307 (Human), P32020 (Mouse), Q07598 (Chick)

Gene ID

6342 (SCP2), 20280 (Scp2), 25541

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of SCP2 / SCPX antibody

SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.

General readings

Stanley,W.A., (2007) Arch. Biochem. Biophys. 461 (1), 50-58

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCP2 / SCPX antibody

  SCP2 mouse monoclonal antibody, clone OTI1E4 (formerly 1E4)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SCP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507247) Mouse IgG1 OTI1E4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCP2 / SCPX antibody

  SCP2 mouse monoclonal antibody, clone OTI1D2 (formerly 1D2)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SCP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507248) Mouse IgG1 OTI1D2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCP2 / SCPX (Center) antibody

  Rabbit polyclonal SCP2 Antibody (Center)  
Western blot analysis of SCP2 Antibody (Center) (Cat. #TA325058) in A2058 cell line lysates (35ug/lane). SCP2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

SCP2 / SCPX antibody

  Rabbit polyclonal Anti-SCP2 Antibody  
Host: Rabbit; Target Name: SCP2; Sample Tissue: Thymus Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCP2 / SCPX antibody

  Rabbit polyclonal Anti-SCP2 Antibody  
WB Suggested Anti-SCP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCP2 / SCPX antibody

  SCP2 mouse monoclonal antibody, clone OTI3H1 (formerly 3H1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SCP2 (RC219802, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SCP2. Mouse IgG2a OTI3H1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCP2 / SCPX antibody

  SCP2 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SCP2 (RC219802, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SCP2. Mouse IgG1 OTI3F5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SCP2 / SCPX antibody


SCP2 antibody Cat.-No AP31972PU-N staining of paraffin embedded Human Liver at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, P
0.1 mg / €350.00
  Acris Antibodies GmbH

SCP2 / SCPX (N-term) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human liver tissue stained with SCP2 Antibody (N-term) Cat.-No AP53816PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SCP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SCP2 - human gene knockout kit via CRISPR

SCP2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SCP2 - human gene knockout kit via CRISPR

SCP2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCP2 - human gene knockout kit via CRISPR

SCP2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SCP2 - human gene knockout kit via CRISPR

SCP2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Scp2 - mouse gene knockout kit via CRISPR

Scp2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Scp2 - mouse gene knockout kit via CRISPR

Scp2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Scp2 - mouse gene knockout kit via CRISPR

Scp2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Scp2 - mouse gene knockout kit via CRISPR

Scp2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SCP2 / SCPX (transcript variant 4)

  Recombinant protein of human sterol carrier protein 2 (SCP2), transcript variant 4  
SCP2 / SCPX Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SCP2 / SCPX (transcript variant 1)

  Recombinant protein of human sterol carrier protein 2 (SCP2), transcript variant 1  
SCP2 / SCPX Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SCP2 (mGFP-tagged) - Human sterol carrier protein 2 (SCP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SCP2 (mGFP-tagged) - Human sterol carrier protein 2 (SCP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

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