Scramblase 1 / PLSCR1 antibody

Principal name

Scramblase 1 / PLSCR1 antibody

Alternative names for Scramblase 1 / PLSCR1 antibody

Phospholipid scramblase 1, PL scramblase 1, MmTRA1b, Ca(2+)-dependent phospholipid scramblase 1, Erythrocyte phospholipid scramblase

SwissProt ID

O15162 (Human), P58195 (Rat), Q9JJ00 (Mouse)

Gene ID

5359 (PLSCR1), 22038 (Plscr1), 117540

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Eq (Equine), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Scramblase 1 / PLSCR1 antibody

Phospholipid scramblase 1 (PLSCR1) is a member of the PLSCR protein family. These proteins are ATP-independent lipid translocators localized to the plasma membrane and is involved in a calcium dependent, nonspecific and rapid redistribution (scrambling) of phospholipids when a perturbation of plasma membrane asymmetry is needed for the cell (e.g. following cell activation, injury, or apoptosis). The expression of PLSCR1 is found in a variety of tissue and can be stress-induced. Upon stimulation (e.g. interferon stimulation), a portion of newly synthesized PLSCR1 is imported into the nucleus (instead of inserted into the plasma membrane) and interacts with D, consistent with a role in gene regulation. PLSCR1 may be closely associated with the pathophysiology underlying infection and inflammation, which manifest marked changes in energy consumption and lipid metabolism.

General readings

Basse F., et al. (1996) J. Biol. Chem. 271:17205-17210Dong B., et al. (2004) J. Virol. 78:8983-8993

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Scramblase 1 / PLSCR1 antibody

  Rabbit Polyclonal antibody to Scramblase1 (phospholipid scramblase 1)  
Sample(30 ug whole cell lysate). A:HeLa S3. 10% SDS PAGE. TA308318 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Scramblase 1 / PLSCR1 antibody

  Rabbit Polyclonal Anti-PLSCR1 Antibody  
Host: Rabbit; Target Name: PLSCR1; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0ug/mlPLSCR1 is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Scramblase 1 / PLSCR1 antibody

  Rabbit Polyclonal Anti-PLSCR1 Antibody  
WB Suggested Anti-PLSCR1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HT1080 cell lysatePLSCR1 is supported by BioGPS gene expression data to be expressed in HT1080 Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Scramblase 1 / PLSCR1 antibody

  Rabbit Polyclonal Anti-PLSCR1 Antibody  
WB Suggested Anti-PLSCR1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Scramblase 1 / PLSCR1 antibody

  Rabbit Polyclonal Scramblase 1 Antibody  
ELISA: Scramblase 1 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Scramblase 1 / PLSCR1 (N-term) (incl. pos. control) antibody

 Detection of Endogenous Scramblase 1. Whole cell lysates of serum starved tumor cells were applied to SDS-PAGE and transferred to a PVDF membrane. The immunoblot was probed with mab Scram1-1E9 (0.5 µg/ ml) for 1h at RT and developed by ECL (exp. time: 30 sec). 
Lane 1: HeLa 
Lane 2: HepG2 
Lane 3: HEK-293 
Lane 4: SY5Y 
Lane 5: Jurkat 
Lane 6: U937 
Lane 7: K562 
Lane 8: THP Mouse IgG1 1E9 Purified Hu WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PLSCR1 - human gene knockout kit via CRISPR

PLSCR1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PLSCR1 - human gene knockout kit via CRISPR

PLSCR1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLSCR1 - human gene knockout kit via CRISPR

PLSCR1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLSCR1 - human gene knockout kit via CRISPR

PLSCR1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Plscr1 - mouse gene knockout kit via CRISPR

Plscr1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Plscr1 - mouse gene knockout kit via CRISPR

Plscr1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Plscr1 - mouse gene knockout kit via CRISPR

Plscr1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Plscr1 - mouse gene knockout kit via CRISPR

Plscr1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Scramblase 1 / PLSCR1 (1-288, His-tag)

Scramblase 1 / PLSCR1 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Scramblase 1 / PLSCR1 (1-288, His-tag)

Scramblase 1 / PLSCR1 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PLSCR1 (mGFP-tagged) - Human phospholipid scramblase 1 (PLSCR1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PLSCR1 (mGFP-tagged) - Human phospholipid scramblase 1 (PLSCR1), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PLSCR1 (Myc-DDK tagged) - Human phospholipid scramblase 1 (PLSCR1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PLSCR1 (Myc-DDK tagged) - Human phospholipid scramblase 1 (PLSCR1) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Plscr1 (GFP-tagged ORF) - Rat phospholipid scramblase 1 (Plscr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Plscr1 (GFP-tagged ORF) - Rat phospholipid scramblase 1 (Plscr1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Plscr1 (Myc-DDK-tagged ORF) - Rat phospholipid scramblase 1 (Plscr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Plscr1 (Myc-DDK-tagged ORF) - Rat phospholipid scramblase 1 (Plscr1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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