SCUBE2 antibody

Principal name

SCUBE2 antibody

Alternative names for SCUBE2 antibody

CEGP1, Signal peptide CUB and EGF-like domain-containing protein 2

SwissProt ID

Q5G872 (Danre), Q9JJS0 (Mouse), Q9NQ36 (Human)

Gene ID

57758 (SCUBE2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of SCUBE2 antibody

SCUBE2 is a 999 amino acid protein that is ubiquitously expressed in adult tissues and belongs to the evolutionarily conserved SCUBE protein family. Containing a CUB domain and nine EGF-like domains, SCUBE2 manifests as a secreted surface-anchored glycoprotein when overexpressed and is considered a novel component of the HH (Hedgehog) signal. The HH signal plays a pivotal role in induction of ventral neuronal and muscle cell types around the midline during vertebrate development. It is suggested that SCUBE2 expression is important in breast cancer progression and may serve as a useful prognostic marker. SCUBE2 forms homo-oligomers and hetero-oligomers with SCUBE1 and SCUBE3. Expressed as three isoforms produced by alternative splicing events, SCUBE2 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

General readings

Yang,R.B., (2002) J. Biol. Chem. 277 (48), 46364-46373

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCUBE2 (Center) antibody

Western blot analysis of SCUBE2 in Daudi cell lysate with SCUBE2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SCUBE2 antibody

WB Suggested Anti-SCUBE2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SCUBE2 antibody

ELISA: SCUBE2 Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

SCUBE2 control peptide

Western blot analysis of SCUBE2 in Daudi cell lysate with SCUBE2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

SCUBE2 antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SCUBE2 (Center) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human breast carcinoma stained with SCUBE2 Antibody (Center) Cat.-No AP53818PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SCUBE2 Antibody (Center N266) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SCUBE2 antibody

Human HeLa; WB Suggested Anti-SCUBE2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Hela cell lysate; SCUBE2 antibody - C-terminal region (ARP49604_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Lysates

Catalog No.    

SCUBE2 overexpression lysate

SCUBE2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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