SDHAF1 antibody

Principal name

SDHAF1 antibody

Alternative names for SDHAF1 antibody

SDH assembly factor 1, Succinate dehydrogenase assembly factor 1 mitochondrial, LYR motif-containing protein 8

SwissProt ID

A6NFY7 (Human), A8PU71 (Bovin), B0K036 (Rat), Q3U276 (Mouse)

Gene ID

644096 (SDHAF1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SDHAF1 antibody

The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).
SDHAF1 Plays an essential role in succinate dehydrogenase complex (SDH) assembly, a complex involved in complex II of the mitochondrial electron transport chain. Probably acts by participating in mitochondrial biosynthesis of iron-sulfur centers for complex II (Probable)

General readings

1. Ghezzi D, Goffrini P, Uziel G, Horvath R, Klopstock T, Lochmüller H, D1Adamo P, Gasparini P, Strom TM, Prokisch H, Invernizzi F, Ferrero I, Zeviani M.
SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy.
Nat Genet. 2009 May 24. [Epub ahead of print].
PMID: 19465911

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SDHAF1 (C-term) antibody

(0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SDHAF1 (C-term) antibody

Western blot analysis of SDHAF1 in 3T3 cell lysate with SDHAF1 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SDHAF1 (1-115, His-tag)

SDHAF1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

SDHAF1 (1-115, His-tag)

SDHAF1 Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

4 Item(s)

per page
  • LinkedIn