SEC62 / TLOC1 antibody

Principal name

SEC62 / TLOC1 antibody

Alternative names for SEC62 / TLOC1 antibody

Translocation protein SEC62, Translocation protein 1

SwissProt ID

P82009 (Canfa), Q5F3A1 (Chick), Q8BU14 (Mouse), Q99442 (Human)

Gene ID

7095 (SEC62)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of SEC62 / TLOC1 antibody

SEC62 Antibody: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translatiol protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with Ri dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.

General readings

Deshaies RJ and Scheckman R. SEC62 encodes a putative membrane protein required for protein translocation in the yeast endoplasmic reticulum. J. Cell Biol. 1989; 109:2653-64.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SEC62 / TLOC1 (C-term) antibody

Western blot analysis of SEC62 in rat brain tissue lysate with SEC62 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SEC62 / TLOC1 (N-term) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue  stained with SEC62 antibody (C-term) Cat.-No AP53834PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SEC62 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SEC62 / TLOC1 (C-term) Control Peptide

50 µg / €160.00
  Acris Antibodies GmbH

SEC62 / TLOC1 antibody

SEC62 / TLOC1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


SEC62 / TLOC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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