SECISBP2 antibody

Principal name

SECISBP2 antibody

Alternative names for SECISBP2 antibody

SECIS-binding protein 2, SBP2, Selenocysteine insertion sequence-binding protein 2

SwissProt ID

Q96T21 (Human), Q9QX72 (Rat)

Gene ID

79048 (SECISBP2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Por (Porcine), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of SECISBP2 antibody

SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. This product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application.

General readings

Papp LV, Lu J, Striebel F, Kennedy D, Holmgren A, Khanna KK. The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function.Mol Cell Biol. 2006 Jul;26(13):4895-910. PMID: 16782878

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SECISBP2 antibody

TA303146 staining of HFF cell lysate with B) 100nM siRNA or A) control siRNA. Detected by chemiluminescence. Data kindly provided by Laura Papp and Kum Kum Khanna, Brisbane, Australia. Goat Purified Bov, Can, Hu, Por E, ICC/IF, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SECISBP2 (Center) antibody

western blot analysis of  SECISBP2 Antibody (Center) Cat.-No AP53835PU-N in HL-60 cell line lysates (35ug/lane). This demonstrates the SECISBP2 antibody detected the SECISBP2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SECISBP2 antibody

Immunofluorescence of purified MaxPab antibody to SECISBP2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

SECISBP2 antibody

Immunofluorescence of purified MaxPab antibody to SECISBP2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SECISBP2 antibody

SECISBP2 Mouse IgG2a 3A7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SECISBP2 antibody

SECISBP2 polyclonal antibody ( Cat # PAB7505 ) staining of HFF cell lysate with B ) 100nM siRNA or A ) control siRNA. Detected by chemiluminescence. Data kindly provided by Laura Papp and Kum Kum Khanna, Brisbane, Australia. Goat Hu E, IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SECISBP2 antibody

Immunohistochemistry: SECISBP2 Antibody [NB100-53795] -  SBP2 Antibody [NB100-53795]- (3ug/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SECISBP2 antibody

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NBP1-92375] Immunohistochemical staining of human thyroid gland shows strong nuclear and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SECISBP2

SECISBP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SECISBP2

SECISBP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SECISBP2 293T Cell Transient Overexpression Lysate(Denatured)

SECISBP2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

SECISBP2 overexpression lysate

SECISBP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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