SEL1L antibody

Principal name

SEL1L antibody

Alternative names for SEL1L antibody

Sel-1L, Protein sel-1 homolog 1, TSA305, Suppressor of lin-12-like protein 1

SwissProt ID

Q80Z70 (Rat), Q9UBV2 (Human), Q9Z2G6 (Mouse)

Gene ID

6400 (SEL1L)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of SEL1L antibody

SEL1L, highly similar to the C elegans sel-1 gene, is a recently cloned human gene whose function is under investigation. SEL1L is differentially expressed in tumors and normal tissues and seems to play a role in tumor growth and aggressiveness. It may be an important negative regulator of the "notch" pathway which acts as a key regulator of the cellular proliferation and specification processes in both vertebrates and invertebrates. SEL1L may function in the protein degradation processes through the ubiquitin-proteosome system and perhaps in regulating important pathways such TGF-beta.It is ubiquitously expressed only in fetal and neoplastic tissues. In normal adult tissues is highly expressed in the acini and in the alpha cells of the pancreas; in general it is highly represented in secretory cells such as plasma cells.

General readings

Schelhaas M, Malmström J, Pelkmans L, Haugstetter J, Ellgaard L, Grünewald K, Helenius A.
Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells.
Cell. 2007 Nov 2;131(3):516-29.
PMID: 17981119

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SEL1L antibody

TA303359 (1µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SEL1L antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using SEL1L antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SEL1L (Center) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human pancreas tissue stained with SEL1L antibody (Center) Cat.-No AP53837PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SEL1L antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SEL1L (N-term) antibody

Western blot analysis of SEL1L Antibody (N-term) Cat.-No AP53838PU-N in T47D cell line lysates (35ug/lane). This demonstrates the SEL1L antibody detected the SEL1L protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SEL1L antibody

SEL1L polyclonal antibody ( Cat # PAB7473 ) ( 1 µg/ml ) staining of HepG2 lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SEL1L antibody

NB100-93463 (1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence Goat IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SEL1L antibody

Immunohistochemistry-Paraffin: SEL1L Antibody [NBP1-81623] Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

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