Selenoprotein K (SELK) antibody

Principal name

Selenoprotein K (SELK) antibody

SwissProt ID

P59798 (Rat), Q2EN82 (Pig), Q32PE3 (Bovin), Q641S4 (Xenla), Q66I79 (Danre), Q9JLJ1 (Mouse), Q9Y6D0 (Human)

Gene ID

58515 (SELK)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Selenoprotein K (SELK) antibody

SELK Antibody: SELK is a selenoprotein, containing a selenocysteine residue at its active site. SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins. SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited

General readings

Lu C, Qiu F, Zhou H, et al. Identification and characterization of selenoprotein K: An antioxidant in cardiomyocytes. FEBS Lett. 2006; 580:5189-97
Shchedrina VA, Everly RA, Zhang Y, et al. Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic homeostasis. J. Biol. Chem. 2011; 286:42937-48.
Huang Z, Hoffmann FW, Norton RL, et al. Selenoprotein K is a novel target of m-calpain, and cleavage is regulated by Toll-like receptor-induced calpastatin in macrophages. J. Biol. Chem. 2011; 286:34830-8.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Selenoprotein K (SELK) (C-term) antibody

Western blot analysis of SELK in A20 cell lysate with SELK antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Selenoprotein K (SELK) (C-term) Control Peptide

Selenoprotein K (SELK)
50 µg / €160.00
  Acris Antibodies GmbH

Selenoprotein K (SELK) antibody

Selenoprotein K (SELK) Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Selenoprotein K (SELK) antibody

Immunohistochemistry-Paraffin: SELK Antibody [NBP1-86120] - Immunohistochemical staining of human salivary gland shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Selenoprotein K (SELK)

Selenoprotein K (SELK) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Selenoprotein K (SELK)

Selenoprotein K (SELK) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Selenoprotein K (SELK)

Selenoprotein K (SELK) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Selenoprotein K (SELK)

Selenoprotein K (SELK) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

8 Item(s)

per page
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