SEMA5A antibody

Principal name

SEMA5A antibody

Alternative names for SEMA5A antibody

Semaphorin-5A, Semaphorin-F, Sema F, SEMAF

SwissProt ID

Q13591 (Human), Q62217 (Mouse)

Gene ID

9037 (SEMA5A), 6489037 (aaeX)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of SEMA5A antibody

Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met. This product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application.

General readings

1. Maraganore DM, de Andrade M, Lesnick TG, Strain KJ, Farrer MJ, Rocca WA, Pant PV, Frazer KA, Cox DR, Ballinger DG. High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet. 2005 Nov;77(5):685-93. Epub 2005 Sep 9.
PMID: 16252231

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SEMA5A antibody

  Goat Anti-SEMA5A (Semaphorin 5A) Antibody  
(4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P
0.1 mg / €360.00
  OriGene Technologies, Inc.

SEMA5A (N-term) antibody

Western blot analysis of anti-Sema5a (N-term) Pab (Cat.#AP12324PU-N) in A2058 cell line lysates (35ug/lane). Sema5a (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SEMA5A (C-term) antibody

Western blot analysis of anti-Semaphorin 5A Pab (C-term) (Cat.#AP12325PU-N) in mouse brain tissue lysates (35ug/lane). Semaphorin 5A(arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


  Recombinant protein of human sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (SEMA5A)  
SEMA5A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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