SENP2 antibody

Principal name

SENP2 antibody

Alternative names for SENP2 antibody

Sentrin-specific protease 2, Smt3ip2, Axam2, KIAA1331, Sentrin/SUMO-specific protease SENP2, SMT3-specific isopeptidase 2

SwissProt ID

Q91ZX6 (Mouse), Q9EQE1 (Rat), Q9HC62 (Human)

Gene ID

59343 (SENP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), Flow Cytometry (F)

Background of SENP2 antibody

SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates. HIPK2 is a desumoylation target for SENP1 which shuttles between the cytoplasm and the nucleus. Mutation analyses reveal that SENP1 contains the nuclear export sequence (NES) within the extreme carboxyl-terminal region, and SENP1 is exported to the cytoplasm in a NES-dependent manner. SENP2 has been implicated as a downregulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. SUMO protease SENP3 reverses the sumoylation of MEF-2 to augment its transcriptional and myogenic activities. SENP5 localizes to the nucleolus and preferentially processes SUMO-3. It is thought to play a role in mitosis and/or cytokinesis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SENP2 antibody

Western Blot: SENP2 Antibody [TA336351] - analysis of SENP2 in human Jurkat (A) and mouse NIH 3T3 (B) cell lysate using SENP3 antibody at 3 ug/ml. Rabbit Purified Hu, Ms P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504810) Mouse IgG1 OTI1C4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504817) Mouse IgG1 OTI1H2 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504865) Mouse IgG2b OTI3F5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504871) Mouse IgG2a OTI1B8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800123) Mouse IgG2a OTI3D3 Purified Hu, Mky F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Anti-SENP2 mouse monoclonal antibody (TA800124) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SENP2(RC208109). Mouse IgG1 OTI1F7 Purified Can, Hu, Mky, Rt F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800125) Mouse IgG1 OTI1D7 Purified Can, Hu, Mky F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800126) Mouse IgG1 OTI5G8 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800127) Mouse IgG1 OTI3E7 Purified Hu, Mky F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800128) Mouse IgG1 OTI3B12 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800130) Mouse IgG1 OTI1D4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800132) Mouse IgG1 OTI6F1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800138) Mouse IgG2a OTI5E1 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Sample(30 ug whole cell lysate). A:293T. B:MOLT4 . 7.5% SDS PAGE. TA308765 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SENP2 antibody

Western blot analysis of extracts from MDA-MB-435cells, using SENP2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SENP2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP2 (RC208109, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP2. Mouse IgG2a OTI2D8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP2 (RC208109, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP2. Mouse IgG2a OTI3H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

Anti-SENP2 mouse monoclonal antibody (TA504867) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SENP2(RC208109). Mouse IgG1 OTI4B3 Purified Can, Hu, Mky, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SENP2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP2 (RC208109, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP2. Mouse IgG1 OTI1H1 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Items 1 to 20 of 37 total

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