SENP5 antibody

Principal name

SENP5 antibody

Alternative names for SENP5 antibody

Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5

SwissProt ID

Q6NXL6 (Mouse), Q96HI0 (Human)

Gene ID

205564 (SENP5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Mky (Monkey), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of SENP5 antibody

SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins, including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates. HIPK2 is a desumoylation target for SENP1 which shuttles between the cytoplasm and the nucleus. Mutation analyses reveal that SENP1 contains the nuclear export sequence (NES) within the extreme carboxyl-terminal region, and SENP1 is exported to the cytoplasm in a NES-dependent manner. SENP2 has been implicated as a downregulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. SUMO protease SENP3 reverses the sumoylation of MEF2 to augment its transcriptional and myogenic activities. SENP5 localizes to the nucleolus and preferentially processes SUMO-3. It is thought to play a role in mitosis and/or cytokinesis. SENP6 localizes to the cytoplasm and releases SUMO-1. Expression of SENP6 is higher in reproductive organs, indicating that it may mediate processes related to reproduction. SENP8 is involved in the release of sentrins.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SENP5 antibody

Western blot analysis of extracts from COS7 cells, using SENP5 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SENP5 antibody

WB Suggested Anti-SENP5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysate Rabbit IgG Purified Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SENP5 antibody

Western blot analysis on COS7 cell lysate using SENP5 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SENP5 antibody

Immunohistochemistry (IHC) analyzes of SENP5 antibody (Cat.-No.: AP06459PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SENP5 (C-term) antibody

(LEFT) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. (RIGHT) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SENP5 Antibody (C-term) (Cat.#AP11240PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SENP5 antibody

SENP5 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SENP5 antibody

Western Blot analysis of SENP5 expression in transfected 293T cell line by SENP5 monoclonal antibody (M01), clone 3C2.

Lane 1: SENP5 transfected lysate(86.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2b 3C2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SENP5 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SENP5 polyclonal antibody ( Cat # PAB2419 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

SENP5 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SENP5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €205.00
  Assay Biotech

SENP5 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SENP5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €310.00
  Assay Biotech

SENP5 antibody

Rat; . Sample Type: 1.Rat Testis cells (200ug) . Primary Dilution: 1:1000. Secondary Antibody: alkaline phosphatase-conjugated anti-rabbit. Secondary Dilution: 1:1000. Image Submitted by: Andreia Carvalho. IBMC-OBF, Portugal . See Customer Feedback tab for detailed information.. .; SENP5 antibody - middle region (ARP55489_P050) in Rat cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SENP5 antibody

Immunohistochemical analysis of SENP5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Mky, Por, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

SENP5 antibody

Immunohistochemical analysis of SENP5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Mky, Por, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

SENP5 antibody

Immunohistochemical analysis of SENP5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Mky, Por, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

SENP5 antibody

SENP5 Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

SENP5 antibody

Western Blot: SENP5 Antibody [NBP1-55439] - This Anti-SENP5 antibody was used in Western Blot of 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

SENP5 antibody

SENP5 Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

SENP5 antibody

SENP5 Rabbit IgG Aff - Purified Hu, Ms E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SENP5

SENP5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SENP5

SENP5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn