Sepiapterin reductase / SPR antibody

Principal name

Sepiapterin reductase / SPR antibody

Alternative names for Sepiapterin reductase / SPR antibody

SDR38C1, EC 1.1.1.153, short chain dehydrogenase/reductase family 38C member 1

SwissProt ID

P18297 (Rat), P35270 (Human), Q17QK8 (Bovin), Q64105 (Mouse), Q7ZY31 (Xenla)

Gene ID

6697 (SPR)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P), Luminex (LMNX)

Background of Sepiapterin reductase / SPR antibody

Sepiapterin reductase (SPR) belongs to the short-chain dehydrogenase/reductase (SDR) family and also reduces various exogenous carbonyl compounds including phenylpropanedione. SPR is an essential enzyme for the biosynthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. Defects in SPR cause DOPA-responsive dystonia defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Recombinant human SPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

General readings

Leu-Semenescu, S., et al. Sleep 33(3): 307-314 (2010)
Schnetz-Boutaud, N.C., et al. Genes Brain Behav. 8(8): 753-757 (2009)
Clot, F., et al. Brain 132 (PT 7): 1753-1763 (2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Sepiapterin reductase / SPR antibody

Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA307911 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Sepiapterin reductase / SPR antibody

Anti-SPR mouse monoclonal antibody (TA501960) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR(RC205679). Mouse IgG1 OTI3D6 Purified Hu, Mky F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

Anti-SPR mouse monoclonal antibody (TA501961) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR(RC205679). Mouse IgG1 OTI3A9 Purified Hu, Mky F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-SPR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501963) Mouse IgG1 OTI2C6 Purified Hu, Mky F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SPR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501983) Mouse IgG1 OTI4F5 Purified Hu, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

Anti-SPR mouse monoclonal antibody (TA501984) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR(RC205679). Mouse IgG1 OTI1F4 Purified Hu, Mky F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

Anti-SPR mouse monoclonal antibody (TA502029) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR(RC205679). Mouse IgG1 OTI3E3 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

SPR ELISA with 3D6 Capture (TA600129) and 3C8 Detection (TA700127) Antibodies. Substrate used: Recombinant Human SPR (TP305679) Mouse IgG1 OTI3C8 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

Sepiapterin reductase / SPR antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (RC205679, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR. Mouse IgG1 OTI3C8 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (RC205679, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR. Mouse IgG1 OTI2F7 Purified Hu, Mky WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Sepiapterin reductase / SPR antibody

SPR ELISA with 1F4 Capture (TA600127) and 3C8 Detection (TA700127) Antibodies. Substrate used: Recombinant Human SPR (TP305679) Mouse IgG1 OTI1F4 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Sepiapterin reductase / SPR antibody

SPR ELISA with 3A9 Capture (TA600128) and 3C8 Detection (TA700127) Antibodies. Substrate used: Recombinant Human SPR (TP305679) Mouse IgG1 OTI3A9 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Sepiapterin reductase / SPR antibody

SPR ELISA with 3D6 Capture (TA600129) and 3C8 Detection (TA700127) Antibodies. Substrate used: Recombinant Human SPR (TP305679) Mouse IgG1 OTI3D6 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Sepiapterin reductase / SPR antibody

SPR ELISA with 3E3 Capture (TA600130) and 3C8 Detection (TA700127) Antibodies. Substrate used: Recombinant Human SPR (TP300619) Mouse IgG1 OTI3E3 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Sepiapterin reductase / SPR (C-term) antibody

Western blot analysis of Sepiapterin reductase (arrow) in mouse liver tissue lysates (35ug/lane) using Sepiapterin reductase / SPR antibody Cat.-No. AP54030PU-N. Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Sepiapterin reductase / SPR antibody

SPR polyclonal antibody (A01), Lot # 060814QCS1. Western Blot analysis of SPR expression in Jurkat. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Sepiapterin reductase / SPR antibody

Western Blot analysis of SPR expression in transfected 293T cell line (H00006697-T01) by SPR MaxPab polyclonal antibody.

Lane1:SPR transfected lysate(28.71 KDa).
Lane2:Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Sepiapterin reductase / SPR antibody

Western Blot analysis of SPR expression in transfected 293T cell line (H00006697-T01) by SPR MaxPab polyclonal antibody.

Lane 1: SPR transfected lysate(28.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Sepiapterin reductase / SPR antibody

Western Blot analysis of SPR expression in transfected 293T cell line (H00006697-T01) by SPR MaxPab polyclonal antibody.

Lane 1: SPR transfected lysate(28.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Sepiapterin reductase / SPR antibody

Sepiapterin reductase / SPR Mouse IgG2a 4F2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Items 1 to 20 of 35 total

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