Serglycin / PRG1 antibody

Principal name

Serglycin / PRG1 antibody

Alternative names for Serglycin / PRG1 antibody

SRGN, Platelet proteoglycan core protein, Secretory granule proteoglycan core protein, Hematopoetic proteoglycan core protein

SwissProt ID

P04917 (Rat), P10124 (Human), P13609 (Mouse)

Gene ID

5552 (SRGN)

Available reactivities

Hu (Human), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Sheep, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of Serglycin / PRG1 antibody

SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Ma, D., et al. Pediatr Blood Cancer 50(5): 1067-1069 (2008)
Kolset, S.O., et al. Glycoconj. J. 25(4): 305-311 (2008)
Theocharis, A.D., et al. J. Biol. Chem. 281(46): 35116-35128 (2006)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3): 1022-1032 (2006)
Raja, S.M., et al. J. Biol. Chem. 280(21): 20752-20761 (2005)

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serglycin / PRG1 antibody

WB Suggested Anti-SRGN Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T Rabbit IgG Purified Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Serglycin / PRG1 (C-term) antibody

Western blot analysis in Hela cell line lysates (35ug/lane) using Serglycin / PRG1 antibody Cat.-No. AP54044PU-N (C-term). This demonstrates the Serglycin antibody detected the Serglycin protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Serglycin / PRG1 antibody

Serglycin / PRG1 Mouse IgG2a 1D8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Serglycin / PRG1 antibody

Transfected 293T; WB Suggested Anti-SRGN Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Transfected 293T; SRGN antibody - middle region (ARP40416_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified Hu, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Serglycin / PRG1 antibody

Serglycin / PRG1 Sheep IgG Purified Hu E
0.5 ml / €400.00
  Novus Biologicals Inc.

Serglycin / PRG1 antibody

Serglycin / PRG1 Rabbit Aff - Purified Hu, Por, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Serglycin / PRG1 antibody

Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886] - Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886] Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Serglycin / PRG1 (28-158, His-tag)

Serglycin / PRG1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Serglycin / PRG1 (28-158, His-tag)

Serglycin / PRG1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Serglycin / PRG1

Serglycin / PRG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Serglycin / PRG1

Serglycin / PRG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Serglycin / PRG1

Serglycin / PRG1 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

Serglycin / PRG1

Serglycin / PRG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Serglycin / PRG1

Serglycin / PRG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Serglycin / PRG1

Serglycin / PRG1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Serglycin / PRG1

Serglycin / PRG1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SRGN overexpression lysate

SRGN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

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