Serglycin / PRG1 antibody

Principal name

Serglycin / PRG1 antibody

Alternative names for Serglycin / PRG1 antibody

SRGN, Platelet proteoglycan core protein, Secretory granule proteoglycan core protein, Hematopoetic proteoglycan core protein

SwissProt ID

P04917 (Rat), P10124 (Human), P13609 (Mouse)

Gene ID

5552 (SRGN), 19073 (Srgn), 56782

Available reactivities

Hu (Human), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of Serglycin / PRG1 antibody

SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Ma, D., et al. Pediatr Blood Cancer 50(5): 1067-1069 (2008)
Kolset, S.O., et al. Glycoconj. J. 25(4): 305-311 (2008)
Theocharis, A.D., et al. J. Biol. Chem. 281(46): 35116-35128 (2006)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3): 1022-1032 (2006)
Raja, S.M., et al. J. Biol. Chem. 280(21): 20752-20761 (2005)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serglycin / PRG1 antibody

  Rabbit Polyclonal Anti-SRGN Antibody  
WB Suggested Anti-SRGN Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T Rabbit IgG Purified Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Serglycin / PRG1 antibody

  Rabbit Polyclonal Anti-SRGN Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (SRGN Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serglycin / PRG1 (C-term) antibody

Western blot analysis in Hela cell line lysates (35ug/lane) using Serglycin / PRG1 antibody Cat.-No. AP54044PU-N (C-term). This demonstrates the Serglycin antibody detected the Serglycin protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Srgn - mouse gene knockout kit via CRISPR

Srgn - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Srgn - mouse gene knockout kit via CRISPR

Srgn - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Srgn - mouse gene knockout kit via CRISPR

Srgn - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Srgn - mouse gene knockout kit via CRISPR

Srgn - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Serglycin / PRG1 (28-158, His-tag)

Serglycin / PRG1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Serglycin / PRG1 (28-158, His-tag)

Serglycin / PRG1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

SRGN overexpression lysate

SRGN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SRGN (mGFP-tagged) - Human serglycin (SRGN), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SRGN (mGFP-tagged) - Human serglycin (SRGN), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SRGN (Myc-DDK tagged) - Human serglycin (SRGN), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SRGN (Myc-DDK tagged) - Human serglycin (SRGN), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Srgn (GFP-tagged) - Mouse serglycin (Srgn), 200 uL, >10^7 TU/mL

Lenti ORF particles, Srgn (GFP-tagged) - Mouse serglycin (Srgn), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Srgn (Myc-DDK-tagged) - Mouse serglycin (Srgn), 200 uL, >10^7 TU/mL

Lenti ORF particles, Srgn (Myc-DDK-tagged) - Mouse serglycin (Srgn), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Srgn (GFP-tagged ORF) - Rat serglycin (Srgn), 200 uL, >10^7 TU/mL

Lenti ORF particles, Srgn (GFP-tagged ORF) - Rat serglycin (Srgn), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Srgn (Myc-DDK-tagged ORF) - Rat serglycin (Srgn), 200 uL, >10^7 TU/mL

Lenti ORF particles, Srgn (Myc-DDK-tagged ORF) - Rat serglycin (Srgn), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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