Serotonin acetylase antibody

Principal name

Serotonin acetylase antibody

Alternative names for Serotonin acetylase antibody

AANAT, AA-NAT, SNAT, Serotonin N-acetyltransferase, Aralkylamine N-acetyltransferase

SwissProt ID

O02785 (Bovin), O88816 (Mouse), O97756 (Macmu), P79774 (Chick), Q16613 (Human), Q29495 (Sheep), Q64666 (Rat)

Gene ID

11298 (Aanat), 25120, 15 (AANAT)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Fi (Fish), Sh (Sheep), Prim (Primate)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Serotonin acetylase antibody

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function, and acts as"the hormone of the night." Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina (1,2). Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans (3).

General readings

General / background references:Li X et al. Molecular rhythms in the pineal gland. Curr Opin Neurobiol 8:648-51 (1998). PubMed PMID: 9811631

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serotonin acetylase antibody

WB: AANAT Antibody - Samples of 1E7 homogenates and bacterially expressed hAANAT were loaded, which contained similar levels of AANAT activity in 65 ug and 2.6 ng of protein. Rabbit Purified Hu, Prim C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin acetylase (N-term) antibody

Western blot analysis of AANAT Antibody (N-term) (Cat. #AP50011PU-N) in Y79 cell line lysates (35 µg/lane). AANAT (arrow) was detected using the purified Pab Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Serotonin acetylase antibody

Western blot analysis of AANAT using AANAT polyclonal antibody ( Cat # PAB12505 ). Samples of 1E7 homogenates and bacterially expressed hAANAT were loaded, which contained similar levels of AANAT activity. Rabbit Hu ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

Serotonin acetylase antibody

Western blot analysis of AANAT expression in A549 (A); PC12 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Serotonin acetylase antibody

Western blot analysis of AANAT expression in A549 (A); PC12 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Serotonin acetylase antibody

Western blot analysis of AANAT expression in A549 (A); PC12 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Serotonin acetylase antibody

Serotonin acetylase Rabbit Biotin Hu, Mky ICC/IF, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

Serotonin acetylase antibody

Serotonin acetylase Rabbit DyLight488 Hu, Mky ICC/IF, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

Serotonin acetylase antibody

Serotonin acetylase Rabbit HRP Hu, Mky ICC/IF, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

Serotonin acetylase antibody

Serotonin acetylase Rabbit Hu, Mky ICC/IF, WB
25 µl / €200.00
  Novus Biologicals Inc.

Serotonin acetylase pThr29 antibody

Western Blot: Serotonin N-acetyltransferase Phosphospecific Antibody [NB120-3439] - Figure 1 shows a Western blot of phospho AA-NAT in transfected 293T cell lysate using NB120-3439. Rabbit IgG Aff - Purified Ms, Rt WB
50 µg / €400.00
  Novus Biologicals Inc.

Serotonin acetylase pSer206 antibody

Western Blot: Serotonin N-acetyltransferase Phosphospecific Antibody [NB120-3440] - Figure 1 shows a Western blot of serotonin AA-NAT in transfected 293T cell lysate using NB120-344. Rabbit IgG Aff - Purified Rt WB
50 µg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Serotonin acetylase

Serotonin acetylase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Serotonin acetylase

Serotonin acetylase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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