Serotonin receptor 1B (HTR1B) antibody

Principal name

Serotonin receptor 1B (HTR1B) antibody

Alternative names for Serotonin receptor 1B (HTR1B) antibody

HTR1DB, 5-hydroxytryptamine receptor 1B, 5-HT-1D-beta

SwissProt ID

O08892 (Cavpo), P28222 (Human), P28334 (Mouse), P28564 (Rat), P49144 (Rabit), P79399 (Pig), Q0EAB5 (Horse), Q588Y6 (Felca)

Gene ID

3351 (HTR1B), 15551 (Htr1b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Fe (Feline), Por (Porcine), Eq (Equine), Mky (Monkey), Bt (Bat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of Serotonin receptor 1B (HTR1B) antibody

The serotonergic system is involved in both pathophysiology and treatment of addiction, depression or mood disorders, appetite control, cardiovascular function, motility of GI tract and sexual function. Serotonin (5-HT) has long been implicated in a number of neurodevelopmental processes including neuronal cell division, migration, neurite outgrowth, and synapse formation which regulate and control some of the above physiological manifestations. Molecular cloning of 5HT receptors have identified a family of closely related genes that encodes several proteins with extensive splice variants exhibiting high degree of amino acid homology (45%-65%) all in the molecular weight range of 40-60 kDa. In brain the 5HT1A binding sites are tightly coupled to oestrous cycle and sex hormone levels (1). Serotonin receptors, also known as 5HT receptors are G-protein coupled rectors (7 transmembrane domains) that elicit the serotonin mediated effects on the above diverse physiological functions. There are at least 7 members of 5HT receptors (5HT1-5HT7), the 5HT1 is further divided in to 6 subtypes (5HT1A-5HT1F) each with multiple variants expressed as a results of alternate splicing or use of alternate initiation codons. Serotonin is reabsorbed by serotonin reuptake transporter which is coupled to sodium/calcium pump.
5HT1A receptors are grouped among the GPCR with characteristic 7TMD. There are several variants isoform of the 5HT1A receptors (5HT1A-5HT1E). The type if signal transduction could be excitatory or inhibitory depending upon the receptor functional coupling to the signal transduction complex. Certain beta arrestins are co-localized with 5HT receptors, where they act in concert with Bark1 or GRK1 and GRK 2 to regulate the expression of the GPCRs. All 5HT receptor proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. 5HT receptors are believed to be associated with other proteins including members of the dopamine receptors and opiod receptors resulting in a significant increase in their apparent molecular weight.

General readings

Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, El Yacoubi M, Vaugeois JM, Nomikos GG, Greengard P. Alterations in 5-HT1B receptor function by p11 in depression-like states. Science. 2006 Jan 6;311(5757):77-80. PMID: 16400147

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serotonin receptor 1B (HTR1B) antibody

TA302601 (2µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 1B (HTR1B) antibody

Western blot analysis of rat hippocampus lysate: 1. Anti-5-Hydroxytryptamine Receptor 1B (extracellular) antibody, (1:400). 2. Anti-5-Hydroxytryptamine Receptor 1B (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Serotonin receptor 1B (HTR1B) antibody

WB Suggested Anti-HTR1B Antibody Titration: 1.25ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 1B (HTR1B) antibody

Western Blot: 5HT1B Receptor Antibody [TA336338] - Analysis of 5HT1BR in human brain lysate with anti-5-HT1BR pcAb (TA336338). A protein band of approximate molecular weight of 40-41kDa was detected. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 1B (HTR1B) (Cytopl. Dom.) antibody

Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

Serotonin receptor 1B (HTR1B) antibody

Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bt, Eq, Hu, Ms, Por, Rt
50 µg / €379.00
  OriGene Technologies, Inc.

Serotonin receptor 1B (HTR1B) Control Peptide

Serotonin receptor 1B (HTR1B)
0.25 mg / €250.00
  Acris Antibodies GmbH

Serotonin receptor 1B (HTR1B) antibody

Serotonin receptor 1B (HTR1B) Rabbit Aff - Purified Ms, Rt E, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Serotonin receptor 1B (HTR1B) antibody

Serotonin receptor 1B (HTR1B) Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Serotonin receptor 1B (HTR1B) antibody

HTR1B polyclonal antibody ( Cat # PAB7035 ) ( 2 µg/ml ) staining of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Serotonin receptor 1B (HTR1B) antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using 5-HT-1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

Serotonin receptor 1B (HTR1B) antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using 5-HT-1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

Serotonin receptor 1B (HTR1B) antibody

Immunofluorescence analysis of A549 cells, using HTR1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

Serotonin receptor 1B (HTR1B) antibody

Immunofluorescence analysis of A549 cells, using HTR1B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

Serotonin receptor 1B (HTR1B) antibody

Human HepG2; WB Suggested Anti-HTR1B Antibody Titration: 1.25ug/ml. Positive Control: HepG2 cell lysate; HTR1B antibody - N-terminal region (AVARP13042_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

Serotonin receptor 1B (HTR1B) antibody

Western Blot: HTR1B Antibody [NB100-41091] - NB100-41091 (2ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Serotonin receptor 1B (HTR1B) antibody

Serotonin receptor 1B (HTR1B) Rabbit Purified Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Serotonin receptor 1B (HTR1B) antibody

Vascular smooth muscle Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Serotonin receptor 1B (HTR1B)

Serotonin receptor 1B (HTR1B) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Serotonin receptor 1B (HTR1B)

Serotonin receptor 1B (HTR1B) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

20 Item(s)

per page
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