Serotonin receptor 3A (HTR3A) antibody

Principal name

Serotonin receptor 3A (HTR3A) antibody

Alternative names for Serotonin receptor 3A (HTR3A) antibody

5-hydroxytryptamine receptor 3A, 5-HT3R, 5-HT3A, Serotonin-gated ion channel receptor

SwissProt ID

O70212 (Cavpo), P23979 (Mouse), P35563 (Rat), P46098 (Human)

Gene ID

3359 (HTR3A), 79246 (Htr3a)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Serotonin receptor 3A (HTR3A) antibody

5-Hydroxytryptamine Receptor 3A (5-HT3A) belongs to the super-family of ligand-gated ion channels. Serotonin receptors, other than 5-HT3 subtype belong to the super-family of G-protein coupled receptors. The 5-HT3 receptor is formed by five subunits arranged around a pore forming unit. Receptors could be either monomeric, such as 5-HT3A or heteromeric entities like 5-HT3A/B. Indeed, the type of channel formed displays different pharmacological and electrophysiological characteristics. To date, five 5-HT3 subunits have been identified 5-HT3A-E, which show variability in the N-terminus and in the transmembrane region. 5-HT3A and 5-HT3B are the best characterized among the different types. In general, 5-HT3 receptors are located in the peripheral and central nervous system, in lymphocytes and intestil enterochromaffine cells. In presyptic neurons, activation of these receptors leads to an increase in intracellular Ca2+ (by both influx and mobilization of intracellular stores), and modulates the release of a number of neurotransmitters and neuropeptides. At the postsyptic level, activation leads to membrane depolarization. The 5-HT3A subunit is expressed in GABAergic and enkephalinergic neurons in the spil dorsal horn thereby marking its possible antinociceptive effect. 5-HT3 receptors have become important targets for which to develop treatments regarding irritable bowel syndrome (IBS), side effects resulting from chemotherapeutic treatment, schizophrenia and bipolar disorder.

General readings

Gatt, J.M., et al. Biol. Psychiatry 68(9):818-824(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Gatt, J.M., et al. Depress Anxiety 27(8):752-759(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)

  1. Quick-Filters:
  2. Cited (1)

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serotonin receptor 3A (HTR3A) antibody

TA302602 (0.3µg/ml) staining of Human Colon lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Western blot analysis of extracts from HT-29 cells, using 5-HT-3A antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Predicted band size: 55 kDa . Positive control: Mouse intestinum tenue tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/375 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using HTR3A antibody at dilution 1/50, on the right is treated with the fusion protein. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Western blot analysis of rat brain (lanes 1 and 3) and mouse brain (lanes 2 and 4) lysates: 1, 2. Anti-5-Hydroxytryptamine Receptor 3A antibody, (1:200). 3, 4. Anti-5-Hydroxytryptamine Receptor 3A antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

WB Suggested Anti-HTR3A Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Western blot analysis of extracts of various cell lines, using HTR3A antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Western Blot: 5HT3A receptor Antibody [TA336339] - Analysis of 5-HT3 Receptor in A) human, B) mouse and C) rat brain tissue lysate using 5-HT3 Receptor antibody at 3 ug/ml. Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

WB Suggested Anti-Htr3a Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Rat Brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 3A (HTR3A) antibody

Anti-5HT3A receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Rabbit IgG Aff - Purified Hu, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Serotonin receptor 3A (HTR3A) antibody

Western blot (WB) analysis of SR-3A antibody (Cat.-No.: AP20471PU-N) in extracts from HT-29 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Serotonin receptor 3A (HTR3A) (428-439) antibody

Immunohistochemistry Image: Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Hu, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Serotonin receptor 3A (HTR3A) (N-term) antibody

Western blot analysis of HTR3A Antibody (N-term) Cat.-No AP52128PU-N in MDA-MB453, K562 cell line lysates (35ug/lane). This demonstrates the HTR3A antibody detected the HTR3A protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Serotonin receptor 3A (HTR3A) antibody

Western blot analysis of Htr3a in A) human, B) mouse and C) rat brain tissue lysate using Htr3a polyclonal antibody ( Cat # PAB0187 ) at 3 µg/ml. Rabbit Hu, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Serotonin receptor 3A (HTR3A) antibody

HTR3A polyclonal antibody ( Cat # PAB7069 ) ( 0.3 µg/ml ) staining of human colon lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Serotonin receptor 3A (HTR3A) antibody

Western blot analysis of extracts from HT-29 cells, using 5-HT-3A Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Serotonin receptor 3A (HTR3A) antibody

Western blot analysis of extracts from HT-29 cells, using 5-HT-3A Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Serotonin receptor 3A (HTR3A) antibody

Serotonin receptor 3A (HTR3A) Rabbit Aff - Purified Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Serotonin receptor 3A (HTR3A) antibody

Human kidney; HTR3A antibody - N-terminal region (AVARP13046_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

Serotonin receptor 3A (HTR3A) antibody

Serotonin receptor 3A (HTR3A) Rabbit IgG Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn